Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021332 | 0.89 | ADRB1 (0.36) | CYP19A1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL9021323 | 0.88 | ADRB1 (0.40) | MAPK1KDM4ERAB9A | |
| SCHEMBL7879572 | 0.83 | TSHR (0.38) | TSHRCYP19A1KMT2AALDH1A1KDM4E | |
| SCHEMBL7875252 | 0.76 | CYP19A1 (0.48) | TSHRMAPK1HTTCYP19A1KMT2A | |
| Hydrochloric Acid SCHEMBL7877064 | 0.74 | KMT2A (0.47) | MAPK1HTTCYP19A1KMT2AALDH1A1 | |
| SCHEMBL7868666 | 0.74 | ADRA2C (0.46) | CYP19A1LMNA | |
| SCHEMBL9021320 | 0.73 | ADRB1 (0.41) | MAPK1HTTKDM4ERAB9A | |
| SCHEMBL7868757 | 0.69 | IDH1 (0.38) | KDM4ERAB9A | |
| SCHEMBL7873921 | 0.69 | MAPK1 (0.42) | MAPK1HTTKMT2AKDM4ERAB9A | |
| SCHEMBL7873770 | 0.69 | CYP26A1 (0.51) | MAPK1HTTALDH1A1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326500-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | ABBOTT LABORATORIES | 2001-12-04 | — | — | US | disclosed |
| US-6215001-B1 | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS, AND ANTIALLERGENS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-04-10 | — | — | US | disclosed |
| US-6031109-A | Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| US-5780642-A | NON-STEROIDAL ANTIINFLAMMATORY AGENT WHICH BLOCKS RELEASE OF ARACHIDONIC ACID FROM PHOSPHOLIPIDS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |
| WO-1995000493-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |