Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 14/20 | 0.70 |
| ▸ | RARG | P13631 | 14/20 | 0.70 |
| ▸ | RARA | P10276 | 12/20 | 0.70 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | PGR | P06401 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.60 |
| ▸ | BLVRB | P30043 | 1/20 | 0.60 |
| ▸ | RXRA | P19793 | 10/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7879855 | 1.00 | RARB (0.70) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL7876455 | 0.88 | RARA (0.54) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL7876451 | 0.88 | RARA (0.54) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL1615595 | 0.83 | RARB (1.00) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL1616018 | 0.83 | RARB (1.00) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL1615597 | 0.83 | RARB (1.00) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL14425237 | 0.83 | MAPT (0.48) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL7876428 | 0.81 | RARB (0.74) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL7876430 | 0.81 | RARB (0.74) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL7882894 | 0.79 | TRPA1 (0.61) | RARBRARGRARACYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326510-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2001-12-04 | — | — | US | disclosed |
| EP-0901462-A1 | BI-AROMATIC COMPOUNDS, COMPOSITIONS CONTAINING THEM AND USES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1999-03-17 | — | — | EP | disclosed |
| WO-1998034909-A1 | BI-AROMATIC COMPOUNDS, COMPOSITIONS CONTAINING THEM AND USES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-08-13 | — | — | WO | disclosed |