Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 3/20 | 0.54 |
| ▸ | RARB | P10826 | 3/20 | 0.54 |
| ▸ | RARG | P13631 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.50 |
| ▸ | MMP1 | P03956 | 3/20 | 0.50 |
| ▸ | MMP2 | P08253 | 3/20 | 0.50 |
| ▸ | MMP9 | P14780 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7876451 | 1.00 | RARA (0.54) | RARARARBRARGCYP3A4MEN1 | |
| SCHEMBL7879849 | 0.88 | RARB (0.70) | RARARARBRARGCYP3A4MEN1 | |
| SCHEMBL7879855 | 0.88 | RARB (0.70) | RARARARBRARGCYP3A4MEN1 | |
| SCHEMBL1615329 | 0.85 | RARB (0.72) | RARARARBRARGCYP3A4MAPT | |
| SCHEMBL1615774 | 0.85 | RARB (0.72) | RARARARBRARGCYP3A4MAPT | |
| SCHEMBL1615332 | 0.85 | RARB (0.72) | RARARARBRARGCYP3A4MAPT | |
| SCHEMBL9187417 | 0.81 | CYP26A1 (0.60) | RARARARBRARGCYP3A4MEN1 | |
| SCHEMBL9187421 | 0.81 | CYP26A1 (0.60) | RARARARBRARGCYP3A4MEN1 | |
| SCHEMBL14425237 | 0.81 | MAPT (0.48) | RARARARBRARGCYP3A4MEN1 | |
| SCHEMBL7878413 | 0.80 | ALDH1A1 (0.58) | RARARARBRARGCYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326510-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2001-12-04 | — | — | US | disclosed |