Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24573787 | 0.76 | TMPRSS4 (0.33) | GAAGLAPOLBTSHR | |
| SCHEMBL6756054 | 0.74 | CES2 (0.41) | GAAALDH1A1GLAPOLBTSHR | |
| SCHEMBL7872269 | 0.74 | SOS1 (0.32) | NOTUM | |
| SCHEMBL23416481 | 0.73 | GAA (0.35) | GAAALDH1A1MAPTRAB9AGLA | |
| SCHEMBL392404 | 0.72 | TSHR (0.52) | GAAALDH1A1MAPTRAB9AGLA | |
| SCHEMBL7657199 | 0.72 | GLA (0.31) | GAAGLAPOLBTSHR | |
| SCHEMBL395557 | 0.72 | KIF11 (0.39) | ALDH1A1 | |
| SCHEMBL7657209 | 0.72 | SMN1; SMN2 (0.39) | GAAALDH1A1GLAPOLBTSHR | |
| SCHEMBL14302780 | 0.72 | GLA (0.31) | GAAGLAPOLBTSHR | |
| SCHEMBL3032982 | 0.72 | CES2 (0.31) | GAAGLAPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326517-B1 | REACTIN AN AROMATIC COMPOUND WITH CARBON MONOXIDE AND AMMONIA | CENTRAL GLASS COMPANY, LIMITED (JP) | 2001-12-04 | — | — | US | disclosed |
| US-6268527-B1 | REACTING TRIFLUOROMETHYL SUBSTITUTED AROMATIC COMPOUND WITH CARBON MONOXIDE AND HYDROXY COMPOUND IN PRESENCE OF METAL COMPOUND AND PHOSPHINE DERIVATIVE TO PRODUCE TRIFLUOROMETHYL SUBSTITUTED BENZOIC ACID DERIVATIVE | CENTRAL GLASS COMPANY, LIMITED (JP) | 2001-07-31 | — | — | US | disclosed |