Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 8/20 | 0.44 |
| ▸ | RXRB | P28702 | 8/20 | 0.44 |
| ▸ | RXRG | P48443 | 7/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | RARB | P10826 | 8/20 | 0.42 |
| ▸ | RARA | P10276 | 7/20 | 0.42 |
| ▸ | RARG | P13631 | 6/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.41 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8102610 | 0.86 | CYP3A4 (0.47) | RXRARXRBRXRGCYP3A4RARB | |
| SCHEMBL7876431 | 0.81 | RXRA (0.67) | RXRARXRBRXRGCYP3A4RARB | |
| SCHEMBL8839222 | 0.80 | RXRA (0.50) | RXRARXRBRXRGCYP3A4RARB | |
| SCHEMBL9255914 | 0.78 | RXRA (0.48) | RXRARXRBRXRGCYP3A4RARB | |
| SCHEMBL8458134 | 0.78 | CYP26A1 (0.65) | RXRARXRBRXRGCYP3A4RARB | |
| SCHEMBL8457432 | 0.77 | CYP3A4 (0.42) | RXRARXRBRXRGCYP3A4RARB | |
| SCHEMBL8459677 | 0.76 | CYP3A4 (0.42) | RXRARXRBRXRGCYP3A4RARB | |
| SCHEMBL8839101 | 0.76 | RXRA (0.48) | RXRARXRBRXRGCYP3A4RARB | |
| SCHEMBL8839361 | 0.76 | RXRA (0.48) | RXRARXRBRXRGCYP3A4RARB | |
| SCHEMBL7880475 | 0.76 | CYP3A4 (0.40) | RXRARXRBRXRGCYP3A4RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326510-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2001-12-04 | — | — | US | disclosed |