SCHEMBL7880384

SCHEMBL7880384

CN(C)c1ccc(C2NCCc3sccc32)cc1

nearest known ligand 0.70

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GID4 Q8IVV7 3/20 0.70
L3MBTL1 Q9Y468 1/20 0.61
GAA P10253 2/20 0.51
ALDH1A1 P00352 3/20 0.45
MAPT P10636 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
PRCP P42785 4/20 0.38
KDM1A O60341 3/20 0.35
DRD3 P35462 1/20 0.35
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4344185 0.83 GID4 (1.00) GID4L3MBTL1MAPTPRCPKDM1A
SCHEMBL2664145 0.80 GID4 (0.71) GID4L3MBTL1GAAPRCPKDM1A
SCHEMBL4339308 0.80 GID4 (0.71) GID4L3MBTL1GAAPRCPKDM1A
SCHEMBL20912502 0.79 GID4 (0.71) GID4L3MBTL1GAAPRCPKDM1A
SCHEMBL20912489 0.79 GID4 (0.71) GID4L3MBTL1GAAPRCPKDM1A
SCHEMBL7889930 0.79 GID4 (0.70) GID4L3MBTL1ALDH1A1KDM1A
SCHEMBL4353119 0.76 GID4 (0.67) GID4L3MBTL1GAAPRCPKDM1A
SCHEMBL7885697 0.76 L3MBTL1 (1.00) GID4L3MBTL1KDM1A
SCHEMBL7885870 0.74 GID4 (0.62) GID4L3MBTL1GAAALDH1A1MAPT
SCHEMBL7880508 0.72 L3MBTL1 (0.68) GID4L3MBTL1PRCPKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6177443-B1 ANTIDIABETIC AGENTS NOVO NORDISK A/S (DK) 2001-01-23 US disclosed
EP-0973778-A1 4,5,6,7-TETRAHYDRO-THIENO 3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2000-01-26 EP disclosed
WO-1998040385-A1 4,5,6,7-TETRAHYDRO-THIENO[3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1998-09-17 WO disclosed