SCHEMBL7885697

SCHEMBL7885697

FC(F)(F)c1ccc(C2NCCc3sccc32)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 1.00
GID4 Q8IVV7 2/20 0.66
KDM1A O60341 3/20 0.55
LHCGR P22888 1/20 0.42
HTR2C P28335 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4357507 0.83 L3MBTL1 (0.71) L3MBTL1GID4KDM1AHTR2C
SCHEMBL7880508 0.81 L3MBTL1 (0.68) L3MBTL1GID4KDM1ALHCGR
SCHEMBL4344185 0.80 GID4 (1.00) L3MBTL1GID4KDM1ALHCGRHTR2C
SCHEMBL2664145 0.80 GID4 (0.71) L3MBTL1GID4KDM1ALHCGR
SCHEMBL4353119 0.80 GID4 (0.67) L3MBTL1GID4KDM1ALHCGR
SCHEMBL31344200 0.79 L3MBTL1 (0.65) L3MBTL1GID4KDM1A
SCHEMBL2359018 0.79 GID4 (0.71) L3MBTL1GID4KDM1A
SCHEMBL20912489 0.79 GID4 (0.71) L3MBTL1GID4KDM1A
SCHEMBL20912502 0.79 GID4 (0.71) L3MBTL1GID4KDM1A
SCHEMBL7880384 0.76 GID4 (0.70) L3MBTL1GID4KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119306742-A Arylpiperidine compound and preparation method, pharmaceutical composition and application thereof 中国药科大学 2025-01-14 CN disclosed
US-6177443-B1 ANTIDIABETIC AGENTS NOVO NORDISK A/S (DK) 2001-01-23 US disclosed
EP-0973778-A1 4,5,6,7-TETRAHYDRO-THIENO 3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2000-01-26 EP disclosed
WO-1998040385-A1 4,5,6,7-TETRAHYDRO-THIENO[3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1998-09-17 WO disclosed