SCHEMBL7880438

SCHEMBL7880438

Bc1ccc([C@H]2CNCCO2)cc1

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.53
DRD3 P35462 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL134338 0.83 DRD2 (0.54) DRD2DRD3
SCHEMBL503006 0.83 DRD2 (0.54) DRD2DRD3
SCHEMBL503067 0.83 DRD2 (0.54) DRD2DRD3
SCHEMBL1638190 0.81
SCHEMBL366065 0.81 DRD2 (0.53) DRD2DRD3
Hydrochloric Acid SCHEMBL917502 0.81 DRD2 (0.53) DRD2DRD3
SCHEMBL82902 0.81 DRD2 (0.53) DRD2DRD3
Hydrochloric Acid SCHEMBL3653333 0.81 DRD2 (0.53) DRD2DRD3
SCHEMBL323436 0.81 DRD2 (0.66) DRD2DRD3
SCHEMBL3404764 0.81 DRD2 (0.53) DRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010104193-A2 INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF MITSUBISHI TANABE PHARMA CORPORATION (JP) 2010-09-16 WO disclosed
WO-2009035159-A1 3-METHYL-2- ( (2S) -2- (4- (3-METHYL-L, 2, 4-0XADIAZ0L-5-YL) PHENYL) MORPHOLINO) -6- (PYRIMIDIN-4-YL) PYRIMIDIN-4 (3H) -ONE AS TAU PROTEIN KINASE INHIBITOR MITSUBISHI TANABE PHARMA CORPORATION (JP) 2009-03-19 WO disclosed