Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL351789 | 0.87 | USP2 (0.50) | USP2THRBHTTCYP1A2CYP3A4 | |
| SCHEMBL14401173 | 0.86 | USP2 (0.47) | USP2THRBHTTCYP1A2CYP3A4 | |
| SCHEMBL2900722 | 0.85 | THRB (0.46) | USP2THRBHTTCYP1A2CYP3A4 | |
| SCHEMBL13966358 | 0.85 | USP2 (0.60) | USP2THRBHTTCYP1A2CYP3A4 | |
| SCHEMBL2853366 | 0.85 | USP2 (0.60) | USP2THRBHTTCYP1A2CYP3A4 | |
| SCHEMBL27933004 | 0.85 | USP2 (0.55) | USP2THRBHTTCYP1A2CYP3A4 | |
| SCHEMBL58458 | 0.83 | USP2 (0.63) | USP2THRBHTTCYP1A2CYP3A4 | |
| SCHEMBL19865136 | 0.83 | USP2 (0.47) | USP2THRBHTTCYP1A2CYP3A4 | |
| SCHEMBL28806984 | 0.83 | USP2 (0.58) | USP2THRBHTTCYP1A2CYP3A4 | |
| SCHEMBL10435643 | 0.83 | USP2 (0.69) | USP2THRBHTTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177070-B1 | REACTIVE ALDEHYDES THAT FORM UNSATURATED COMPOUNDS | LYNCH UNA E (US) | 2001-01-23 | — | — | US | disclosed |