Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20262946 | 0.95 | MEN1 (0.52) | THRBTSHRMAPK1MEN1KMT2A | |
| SCHEMBL7206346 | 0.95 | MEN1 (0.52) | THRBTSHRMAPK1MEN1KMT2A | |
| SCHEMBL350840 | 0.86 | TSHR (0.53) | THRBTSHRMAPK1MEN1KMT2A | |
| SCHEMBL7936270 | 0.86 | THRB (0.53) | THRBTSHRMAPK1USP2ALDH1A1 | |
| SCHEMBL9736299 | 0.85 | HSD17B10 (0.56) | THRBTSHRMEN1KMT2AUSP2 | |
| SCHEMBL28238169 | 0.85 | TSHR (0.41) | THRBTSHRMAPK1MEN1KMT2A | |
| SCHEMBL7880864 | 0.85 | USP2 (0.45) | THRBTSHRMEN1KMT2AUSP2 | |
| SCHEMBL7777482 | 0.83 | TSHR (0.39) | TSHRMAPK1MEN1KMT2AUSP2 | |
| SCHEMBL30519837 | 0.83 | TSHR (0.39) | TSHRMAPK1MEN1KMT2AUSP2 | |
| SCHEMBL795575 | 0.83 | USP2 (0.48) | THRBTSHRMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111615528-A | Dendrimer delivery systems and methods of use thereof | 约翰霍普金斯大学 | 2020-09-01 | — | — | CN | claimed |
| US-9334459-B2 | Method and composition for preventing oxidation | MIDWEST INDUSTRIAL SUPPLY, INC. (US) | 2016-05-10 | — | — | US | claimed |
| US-9029445-B2 | Method and composition for preventing oxidation | MIDWEST INDUSTRIAL SUPPLY, INC. (US) | 2015-05-12 | — | — | US | claimed |
| US-9018287-B2 | Method and composition for preventing oxidation | MIDWEST INDUSTRIAL SUPPLY, INC. (US) | 2015-04-28 | — | — | US | claimed |
| US-20140331551-A1 | METHOD AND COMPOSITION FOR PREVENTING OXIDATION | THE HUNTINGTON NATIONAL BANK | 2014-11-13 | — | — | US | claimed |
| US-20140323626-A1 | METHOD AND COMPOSITION FOR PREVENTING OXIDATION | MIDWEST INDUSTRIAL SUPPLY, INC. (US) | 2014-10-30 | — | — | US | claimed |
| WO-2014176537-A1 | METHOD AND COMPOSITION FOR PREVENTING OXIDATION | MIDWEST INDUSTRIAL SUPPLY, INC. (US) | 2014-10-30 | — | — | WO | claimed |
| CN-111615528-A | Dendrimer delivery systems and methods of use thereof | 约翰霍普金斯大学 | 2020-09-01 | — | — | CN | disclosed |
| US-20150252402-A1 | Chemoenzymatic Synthesis of Trehalose Analogs | CENTRAL MICHIGAN UNIVERSITY | 2015-09-10 | — | — | US | disclosed |
| WO-2014176537-A1 | METHOD AND COMPOSITION FOR PREVENTING OXIDATION | MIDWEST INDUSTRIAL SUPPLY, INC. (US) | 2014-10-30 | — | — | WO | disclosed |
| EP-2149816-B1 | METHOD OF MANUFACTURING AN ELECTROCHROMIC DISPLAY ELEMENT | KONICA MINOLTA HOLDINGS INC (JP) | 2014-05-07 | — | — | EP | disclosed |
| EP-2149816-A1 | METHOD FOR PRODUCTION OF DISPLAY ELEMENT | Konica Minolta Holdings, Inc. (JP) | 2010-02-03 | — | — | EP | disclosed |
| EP-0733045-B1 | 4,6-DIANILINO-PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2001-08-16 | — | — | EP | disclosed |
| US-5880130-A | TREATMENT OF CELL-PROLIFERATION DISEASES | ZENECA LIMITED (GB) | 1999-03-09 | — | — | US | disclosed |
| EP-0668792-A1 | PRE-TREATMENT OF NATURAL GAS TO BE CONDENSED TO LIQUEFIED NATURAL GAS (LNG) | NORSK HYDRO A/S (NO) | 1995-08-30 | — | — | EP | disclosed |
| WO-1994011090-A1 | PRE-TREATMENT OF NATURAL GAS TO BE CONDENSED TO LIQUEFIED NATURAL GAS (LNG) | NORSK HYDRO A.S (NO) | 1994-05-26 | — | — | WO | disclosed |
| US-4045516-A | Solid curable polyene compositions containing a polythiol | W. R. GRACE & CO. (US) | 1977-08-30 | — | — | US | disclosed |
| US-4018940-A | Process for forming solder resistant photoresist coatings | W. R. GRACE & CO. (US) | 1977-04-19 | — | — | US | disclosed |
| US-4017371-A | Solid radiation curable polyene compositions containing liquid polythiols and solid styrene-allyl copolymer based polyenes | W. R. GRACE & CO. (US) | 1977-04-12 | — | — | US | disclosed |
| US-4006270-A | Solid curable polyene compositions and method of coating therewith | W. R. GRACE & CO. (US) | 1977-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150252402-A1 | Chemoenzymatic Synthesis of Trehalose Analogs | TREH, TALDO1, TKT | THRB 1214/4885TSHR 1887/4885MAPK1 2592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.