Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | RHEB | Q15382 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5349501 | 0.86 | METAP2 (0.43) | METAP2METAP1ENPP1GRIN2BPTGDR2 | |
| Hypoxanthine SCHEMBL10718864 | 0.85 | ALDH1A1 (0.46) | METAP2METAP1 | |
| SCHEMBL7771672 | 0.84 | METAP2 (0.42) | METAP2METAP1ENPP1GRIN2BPTGDR2 | |
| SCHEMBL788792 | 0.84 | METAP2 (0.42) | METAP2METAP1ENPP1GRIN2BPTGDR2 | |
| SCHEMBL4521139 | 0.84 | METAP2 (0.42) | METAP2METAP1ENPP1GRIN2BPTGDR2 | |
| SCHEMBL19207483 | 0.80 | METAP2 (0.39) | METAP2METAP1ENPP1GRIN2BPTGDR2 | |
| SCHEMBL28203630 | 0.78 | METAP2 (0.38) | METAP2METAP1ENPP1GRIN2B | |
| SCHEMBL7576752 | 0.77 | METAP2 (0.42) | METAP2METAP1ENPP1NPY5R | |
| SCHEMBL14125937 | 0.77 | KDM4E (0.46) | METAP2METAP1KDM4ECYP2C9HSD17B10 | |
| SCHEMBL18114688 | 0.74 | KDM4E (0.46) | KDM4ECYP3A4CYP2C9PTPRBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114253040-A | Light modulation device | 江苏集萃智能液晶科技有限公司 | 2022-03-29 | — | — | CN | claimed |
| CN-106543183-A | The synthetic method of 2,3 dibromo of medical body, 5 methyl purine, 6 carboxylic acid, ethyl ester | 无锡乾浩生物医药有限公司 | 2017-03-29 | — | — | CN | claimed |
| CN-104193745-B | A kind of imidazopyrimidine carboxylic acid compound and preparation method thereof | 斯芬克司药物研发（天津）股份有限公司 | 2016-09-28 | — | — | CN | claimed |
| CN-104193745-A | Imidazolopyrimidine carboxylic acid type compound and preparation method thereof | SPHINX SCIENT LAB CORP | 2014-12-10 | — | — | CN | claimed |
| EP-2616469-A1 | INHIBITORS OF PI3K-DELTA AND METHODS OF THEIR USE AND MANUFACTURE | Exelixis, Inc. (US) | 2013-07-24 | — | — | EP | claimed |
| WO-2012037226-A1 | INHIBITORS OF PI3K-DELTA AND METHODS OF THEIR USE AND MANUFACTURE | EXELIXIS, INC. (US) | 2012-03-22 | — | — | WO | claimed |
| EP-1649857-A2 | New use of glutamate antagonists for the treatment of cancer | Ikonomidou, Hrissanthi (DE) | 2006-04-26 | — | — | EP | claimed |
| US-20050054650-A1 | Use of glutamate antagonists for the treatment of cancer | IKONOMIDOU HRISSANTHI (DE) | 2005-03-10 | — | — | US | claimed |
| EP-1124553-A1 | NEW USE OF GLUTAMATE ANTAGONISTS FOR THE TREATMENT OF CANCER | Ikonomidou, Hrissanthi (DE) | 2001-08-22 | — | — | EP | claimed |
| EP-1002535-A1 | New use of glutamate antagonists for the treatment of cancer | Ikonomidou, Hrissanthi (DE) | 2000-05-24 | — | — | EP | claimed |
| EP-0701446-A4 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORP (US) | 1997-04-23 | — | — | EP | claimed |
| EP-0621788-A4 | HEMOREGULATORY PEPTIDES. | SMITHKLINE BEECHAM CORP (US) | 1997-03-05 | — | — | EP | claimed |
| EP-0725651-A4 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORP (US) | 1997-03-05 | — | — | EP | claimed |
| EP-0725651-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1996-08-14 | — | — | EP | claimed |
| EP-0701446-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1996-03-20 | — | — | EP | claimed |
| WO-1995011693-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-05-04 | — | — | WO | claimed |
| WO-1994027627-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1994-12-08 | — | — | WO | claimed |
| EP-0621788-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1994-11-02 | — | — | EP | claimed |
| CN-1077960-A | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORP (US) | 1993-11-03 | — | — | CN | claimed |
| WO-1993013789-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-07-22 | — | — | WO | claimed |