Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.30 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL788792 | 0.83 | METAP2 (0.42) | METAP2METAP1ENPP1NPY5RPKN1 | |
| SCHEMBL4521139 | 0.79 | METAP2 (0.42) | METAP2METAP1ENPP1NPY5R | |
| SCHEMBL5349501 | 0.77 | METAP2 (0.43) | METAP2METAP1ENPP1NPY5RPKN1 | |
| SCHEMBL788096 | 0.77 | METAP2 (0.43) | METAP2METAP1ENPP1NPY5R | |
| SCHEMBL28203630 | 0.76 | METAP2 (0.38) | METAP2METAP1ENPP1PKN1PKN2 | |
| SCHEMBL7771672 | 0.76 | METAP2 (0.42) | METAP2METAP1ENPP1NPY5R | |
| SCHEMBL19207483 | 0.72 | METAP2 (0.39) | METAP2METAP1ENPP1NPY5R | |
| SCHEMBL5632 | 0.72 | NUDT1 (0.50) | METAP2METAP1NPY5R | |
| SCHEMBL277596 | 0.72 | METAP2 (0.51) | METAP2METAP1ENPP1NPY5R | |
| SCHEMBL30388675 | 0.72 | NUDT1 (0.50) | METAP2METAP1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020197253-A1 | Compositions and methods for promoting or inhibiting NDPK | DUKE UNIVERSITY | 2002-12-26 | — | — | US | disclosed |
| WO-2002094376-A2 | COMPOSITIONS AND METHODS FOR PROMOTING OR INHIBITING NDPK | DUKE UNIVERSITY (US) | 2002-11-28 | — | — | WO | disclosed |