Sugi Predict

Sugi Predict / Compounds / SCHEMBL7881069

SCHEMBL7881069

SCHEMBL7881069

COC(=O)[C@@H](COC(C)(C)C)N(CCN)C(=O)OCc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EPOR P19235 2/20 0.42
▸ CTSL P07711 1/20 0.40
▸ CTSS P25774 1/20 0.40
▸ CTSK P43235 1/20 0.40
▸ ABCB1 P08183 2/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ CCR6 P51684 1/20 0.37
▸ PAX8 Q06710 1/20 0.37
▸ ALDH1A1 P00352 2/20 0.37
▸ PRSS1 P07477 1/20 0.37
▸ TPSAB1 Q15661 1/20 0.37
▸ SYK P43405 1/20 0.36
▸ LTA4H P09960 1/20 0.35
▸ L3MBTL1 Q9Y468 2/20 0.35
▸ CYP1A2 P05177 1/20 0.35
▸ CYP3A4 P08684 1/20 0.35
▸ RECQL P46063 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29171346 0.91 ALDH1A1 (0.39) EPORCTSLCTSSCTSKABCB1
SCHEMBL29171347 0.91 ALDH1A1 (0.39) EPORCTSLCTSSCTSKABCB1
SCHEMBL12189909 0.85 EPOR (0.46) EPORABCB1CCR6PAX8ALDH1A1
SCHEMBL2525899 0.84 SYK (0.47) CTSLCTSSCTSKSMN1; SMN2TPSAB1
SCHEMBL30841389 0.83 EPOR (0.47) EPORCTSLABCB1CCR6PAX8
SCHEMBL30841325 0.81 EPOR (0.50) EPORABCB1CCR6PAX8
SCHEMBL16408139 0.80 ALDH1A1 (0.41) CTSLCTSSCTSKABCB1SMN1; SMN2
SCHEMBL30841404 0.79 CA12 (0.44) EPORABCB1ALDH1A1LTA4HLMNA
SCHEMBL12514163 0.78 ADRB2 (0.39) CTSSCTSKL3MBTL1POLB
SCHEMBL30841321 0.77 ITGA4 (0.46) EPORCTSLSMN1; SMN2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109928971-B Aryl substituted aminotetrahydropyrans and uses thereof 广东东阳光药业股份有限公司 2024-01-16 — — CN disclosed
US-20120016126-A1 METHOD FOR MANUFACTURING DIPEPTIDYL PEPTIDASE-IV INHIBITOR AND INTERMEDIATE DONG-A PHARMACEUTICAL. CO., LTD (KR) 2012-01-19 — — US disclosed
US-20120016125-A1 METHOD FOR PREPARING DIPEPTIDYL PEPTIDASE-IV INHIBITOR AND INTERMEDIATE DONG-A PHARMACEUTICAL. CO., LTD (KR) 2012-01-19 — — US disclosed
WO-2010114291-A2 IMPROVED METHOD FOR PREPARING DIPEPTIDYL PEPTIDASE-IV INHIBITOR AND INTERMEDIATE 동아제약 주식회사 (KR) 2010-10-07 — — WO disclosed
WO-2010114292-A2 IMPROVED METHOD FOR MANUFACTURING DIPEPTIDYL PEPTIDASE-IV INHIBITOR AND INTERMEDIATE 동아제약 주식회사 (KR) 2010-10-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120016126-A1 METHOD FOR MANUFACTURING DIPEPTIDYL PEPTIDASE-IV INHIBITOR AND INTERMEDIATE DPP4, DPP3, DPP7 EPOR 1517/4885CTSL 113/4885CTSS 584/4885
US-20120016125-A1 METHOD FOR PREPARING DIPEPTIDYL PEPTIDASE-IV INHIBITOR AND INTERMEDIATE DPP4, DPP3, DPP7 EPOR 1710/4885CTSL 119/4885CTSS 460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.