Benzene

Benzene

SCHEMBL788131

[SiH3]Cl.c1ccccc1.c1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
TP53 P04637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL9240933 1.00
Benzene SCHEMBL11652010 0.93
Benzene SCHEMBL8021516 0.71 TSHR (1.00) TSHRTP53
SCHEMBL1086976 0.71 TSHR (1.00) TSHRTP53
SCHEMBL10908 0.71
Benzene SCHEMBL8022649 0.71 TSHR (1.00) TSHRTP53
Benzene SCHEMBL8576855 0.71 TSHR (1.00) TSHRTP53
SCHEMBL1112772 0.71 TSHR (1.00) TSHRTP53
SCHEMBL3480976 0.71
Benzene SCHEMBL8430159 0.71 TSHR (1.00) TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3768733-A1 SILICON-TERMINATED TELECHELIC POLYOLEFIN COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME Dow Global Technologies LLC (US) 2021-01-27 EP claimed
US-20210017311-A1 SILICON-TERMINATED TELECHELIC POLYOLEFIN COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC 2021-01-21 US claimed
WO-2019182993-A1 SILICON-TERMINATED TELECHELIC POLYOLEFIN COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-26 WO claimed
US-12037462-B2 Polyolefin-polydiorganosiloxane block copolymer and method for the synthesis thereof DOW GLOBAL TECHNOLOGIES LLC (US) 2024-07-16 US disclosed
US-11814555-B2 Hot melt adhesive compositions containing polyolefin-polydiorganosiloxane copolymers and methods for the preparation and use thereof DOW SILICONES CORPORATION (US) 2023-11-14 US disclosed
EP-3768793-B1 POLYORGANOSILOXANE HOT MELT ADHESIVE COMPOSITIONS CONTAINING POLYOLEFIN - POLYDIORGANOOSILOXANE COPOLYMERS AND METHODS FOR THE PREPARATION AND USE THEREOF DOW SILICONES CORP (US) 2023-09-27 EP disclosed
EP-3768792-B1 HOT MELT ADHESIVE COMPOSITION CONTAINING A POLYOLEFIN - POLYDIORGANOSILOXANE COPOLYMER AND METHODS FOR THE PREPARATION AND USE THEREOF DOW SILICONES CORP (US) 2023-09-20 EP disclosed
US-11702512-B2 Polysiloxane resin-polyolefin copolymer and methods for the preparation and use thereof DOW SILICONES CORPORATION (US) 2023-07-18 US disclosed
EP-3768765-B1 POLYOLEFIN-POLYDIORGANOSILOXANE BLOCK COPOLYMER AND HYDROSILYLATON REACTION METHOD FOR THE SYNTHESIS THEREOF DOW SILICONES CORP (US) 2023-05-17 EP disclosed
US-11332583-B2 Polyolefin-polydiorganosiloxane block copolymer and hydrosilylation reaction method for the synthesis thereof DOW SILICONES CORPORATION (US) 2022-05-17 US disclosed
US-11193051-B2 Hot melt adhesive composition containing a polyolefin-polydiorganosiloxane copolymer and methods for the preparation and use thereof DOW SILICONES CORPORATION (US) 2021-12-07 US disclosed
WO-2019182721-A1 POLYOLEFIN-POLYDIORGANOSILOXANE BLOCK COPOLYMER AND HYDROSILYLATON REACTION METHOD FOR THE SYNTHESIS THEREOF DOW SILICONES CORPORATION (US) 2019-09-26 WO disclosed
WO-2019182992-A1 PROCESS FOR FUNCTIONALIZATION OF ORGANO-ZINC COMPOUNDS WITH HALOSILANES USING BASIC NITROGEN CONTAINING HETEROCYCLES AND SILYL-FUNCTIONALIZED COMPOUNDS PREPARED THEREBY DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-26 WO disclosed
WO-2019182718-A1 HOT MELT ADHESIVE COMPOSITION CONTAINING A POLYOLEFIN - POLYDIORGANOSILOXANE COPOLYMER AND METHODS FOR THE PREPARATION AND USE THEREOF DOW SILICONES CORPORATION (US) 2019-09-26 WO disclosed
WO-2019182720-A1 POLYOLEFIN-POLYDIORGANOSIIOXANE BLOCK COPOLYMER AND METHOD FOR THE SYNTHESIS THEREOF DOW SILICONES CORPORATION (US) 2019-09-26 WO disclosed
WO-2019182993-A1 SILICON-TERMINATED TELECHELIC POLYOLEFIN COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-26 WO disclosed
WO-2019182719-A1 POLYORGANOSILOXANE HOT MELT ADHESIVE COMPOSITIONS CONTAINING POLYOLEFIN - POLYDIORGANOOSILOXANE COPOLYMERS AND METHODS FOR THE PREPARATION AND USE THEREOF DOW SILICONES CORPORATION (US) 2019-09-26 WO disclosed
US-8575381-B2 Trihydridosilyl-terminated polysilanes and methods of preparation GELEST TECHNOLOGIES, INC. (US) 2013-11-05 US disclosed
US-20120071678-A1 TRIHYDRIDOSILYL-TERMINATED POLYSILANES AND METHODS OF PREPARATION GELEST TECHNOLOGIES, INC. (US) 2012-03-22 US disclosed
EP-0516144-A1 Organopolysilsesquioxane and method for its preparation Dow Corning Toray Silicone Company, Limited (JP) 1992-12-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071678-A1 TRIHYDRIDOSILYL-TERMINATED POLYSILANES AND METHODS OF PREPARATION SI, STT3A, STT3B TSHR 3039/4885TP53 2742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.