SCHEMBL788147

SCHEMBL788147

O=S(=O)(Cl)c1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 2/20 0.44
HTT P42858 3/20 0.43
TSHR P16473 3/20 0.43
MAPT P10636 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PKM P14618 1/20 0.39
MAPK1 P28482 2/20 0.39
CYP3A4 P08684 1/20 0.39
TDP1 Q9NUW8 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.35
ALDH1A1 P00352 3/20 0.34
CES1 P23141 2/20 0.33
AHR P35869 1/20 0.33
HSD17B10 Q99714 1/20 0.33
LMNA P02545 1/20 0.33
PFKFB3 Q16875 1/20 0.33
NR3C1 P04150 1/20 0.33
CCR1 P32246 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31556483 1.00 TRPV4 (0.44) TRPV4HTTTSHRMAPTSMN1; SMN2
SCHEMBL10532523 0.93 TSHR (0.40) TRPV4HTTTSHRMAPTSMN1; SMN2
SCHEMBL3415632 0.80 HTT (0.43) HTTTSHRMAPTSMN1; SMN2PKM
SCHEMBL2051715 0.80 HTT (0.43) HTTTSHRMAPTSMN1; SMN2PKM
SCHEMBL3550070 0.79 LMNA (0.43) TRPV4HTTTSHRMAPTSMN1; SMN2
SCHEMBL8764082 0.79 TSHR (0.40) TRPV4HTTTSHRMAPTSMN1; SMN2
SCHEMBL184577 0.79 TRPV4 (0.40) TRPV4HTTTSHRMAPK1CYP3A4
SCHEMBL16555423 0.79 TRPV4 (0.40) TRPV4HTTTSHRTDP1ALDH1A1
SCHEMBL29519135 0.78 TSHR (0.53) TSHRTDP1ALDH1A1LMNA
SCHEMBL18457 0.78 TSHR (0.53) TSHRTDP1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
EP-0021592-A1 Phenylsulphonamide derivatives, a process for their preparation and their use as medicines BEECHAM - WUELFING GmbH & Co. KG (DE) 1981-01-07 EP claimed
WO-2025075722-A1 PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, AND CATALYST FOR POLYMERIZAING OLEFINS FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2025-04-10 WO disclosed
US-20250115687-A1 PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, AND CATALYST FOR POLYMERIZAING OLEFINS FORMOSA PLASTICS CORP USA (US) 2025-04-10 US disclosed
US-11500247-B2 Liquid crystal sensor PLATYPUS TECHNOLOGIES, LLC (US) 2022-11-15 US disclosed
US-20200409221-A1 LIQUID CRYSTAL SENSOR PLATYPUS TECHNOLOGIES, LLC 2020-12-31 US disclosed
EP-2758399-B1 N-[4-(1H-PYRAZOLO[3,4-B]PYRAZIN-6-YL)-PHENYL]-SULFONAMIDES AND THEIR USE AS PHARMACEUTICALS SANOFI SA (FR) 2017-11-15 EP disclosed
US-20170212088-A1 DETECTION OF GAS-PHASE ANALYTES USING LIQUID CRYSTALS PLATYPUS TECHNOLOGIES, LLC 2017-07-27 US disclosed
US-9575037-B2 Detection of gas-phase analytes using liquid crystals PLATYPUS TECHNOLOGIES, LLC (US) 2017-02-21 US disclosed
EP-2675526-B1 NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS VIFOR (INTERNATIONAL) AG (CH) 2017-02-01 EP disclosed
US-20160274084-A1 DETECTION OF VAPOR PHASE COMPOUNDS BY CHANGES IN PHYSICAL PROPERTIES OF A LIQUID CRYSTAL PLATYPUS TECHNOLOGIES, LLC 2016-09-22 US disclosed
US-4178330-A Haloaryl halobenzenesulfonate flame retardants VELSICOL CHEMICAL CORPORATION (US) 1979-12-11 US disclosed
EP-0001017-A1 Haloaryl halobenzenesulfonates, their production and their use as flame retardants Velsicol Chemical Corporation (US) 1979-03-07 EP disclosed
US-4141808-A Manganese carbonyl-sulfonyl chloride photoinitiators for radiation polymerizable unsaturated compounds EASTMAN KODAK COMPANY (US) 1979-02-27 US disclosed
US-4136253-A ANTIBIOTICS PFIZER INC. (US) 1979-01-23 US disclosed
US-4051144-A ADRENERGIC BLOCKING AGENTS CHARLES E. FROSST & CO. (CA) 1977-09-27 US disclosed
US-4042586-A ADRENERGIC BLOCKING AGENTS MERCK SHARP & DOHME (I.A.) CORPORATION (US) 1977-08-16 US disclosed
US-4031125-A 3-Sulfonate ester of 2,3-dihydroxypropylamine MERCK & CO., INC. (US) 1977-06-21 US disclosed
US-3962338-A Novel methods and compounds employed therein MERCK & CO., INC. (US) 1976-06-08 US disclosed
US-3946009-A ADRENERGIC BLOCKING AGENTS MERCK SHARP & DOHME (I.A.) CORPORATION (US) 1976-03-23 US disclosed