Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.37 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7887364 | 1.00 | ABCC9 (0.37) | ABCC9ABCC8KCNJ11KCNJ8KDM1A | |
| SCHEMBL31730065 | 0.77 | DDB1 (0.46) | ABCC9ABCC8KCNJ11KCNJ8KDM1A | |
| SCHEMBL21805277 | 0.75 | POLB (0.45) | ABCC9ABCC8KCNJ11KCNJ8KDM1A | |
| SCHEMBL31232304 | 0.72 | POLB (0.35) | KDM1APOLBHPGDALDH1A1KMT2A | |
| SCHEMBL537358 | 0.72 | DRD2 (0.57) | KDM1A | |
| SCHEMBL2117348 | 0.72 | DRD2 (0.57) | KDM1A | |
| SCHEMBL2179017 | 0.72 | CA2 (0.46) | POLBKDM4EALDH1A1TSHRRAB9A | |
| SCHEMBL2033480 | 0.71 | POLB (0.44) | KDM1APOLBHPGDKDM4EALDH1A1 | |
| SCHEMBL671164 | 0.70 | CHRNB4 (0.40) | POLBKMT2AMEN1 | |
| SCHEMBL1893123 | 0.70 | KDM1A (0.47) | KDM1APOLBHPGDALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010114179-A1 | 3-[1,4]OXAZEPANE-4-PYRIMIDONE DERIVATIVES | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-10-07 | — | — | WO | disclosed |