SCHEMBL78844

SCHEMBL78844

C=CC(=O)OCC=CN=C=O

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.39
ALDH1A1 P00352 4/20 0.39
TP53 P04637 3/20 0.39
HIF1A Q16665 3/20 0.39
CYP3A4 P08684 2/20 0.39
HSD17B10 Q99714 1/20 0.39
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HPGD P15428 1/20 0.36
THRB P10828 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10598364 0.84 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL4664671 0.79 GSTP1 (0.32)
SCHEMBL19846628 0.77 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29417881 0.77 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL19620226 0.77 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL11633090 0.77 ALOX15 (0.38)
SCHEMBL72966 0.76 TSHR (0.40) TSHRALDH1A1THRB
SCHEMBL5163644 0.76 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9064001 0.72
SCHEMBL931344 0.72 TSHR (0.45) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 379 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113227301-B Composition made of epoxy resin and polyurethane 博斯蒂克股份公司 2023-05-12 CN claimed
CN-113227301-A Composition made of epoxy resin and polyurethane 博斯蒂克股份公司 2021-08-06 CN claimed
EP-2100907-B1 RESIN COMPOSITION FOR PRINTING PLATE ASAHI KASEI E MATERIALS CORP (JP) 2013-02-20 EP claimed
US-8129494-B2 Resin composition for printing plate ASAHI KASEI E-MATERIALS CORPORATION (JP) 2012-03-06 US claimed
US-7829261-B2 Method for making a lithographic plate KODAK GRAPHIC COMMUNICATIONS GMBH (BG) 2010-11-09 US claimed
US-20100093119-A1 RESIN COMPOSITION FOR PRINTING PLATE ASAHI KASEI E-MATERIALS CORPORATION (JP) 2010-04-15 US claimed
EP-2100907-A1 RESIN COMPOSITION FOR PRINTING PLATE Asahi Kasei Chemicals Corporation (JP) 2009-09-16 EP claimed
US-20090022961-A1 INTERLAYER FOR LITHOGRAPHIC PLATES EASTMAN KODAK COMPANY 2009-01-22 US claimed
EP-1791700-B1 PROCESS FOR THE PRODUCTION OF A LITHOGRAPHIC PRINTING PLATE KODAK GRAPHIC COMM GMBH (DE) 2008-05-28 EP claimed
US-20070254238-A1 Method for Making a Lithographic Plate KODAK POLYCHROME GRAPHICS, GMBH (DE) 2007-11-01 US claimed
US-4609706-A OXIDATIVELY CURABLE SCM CORPORATION (US) 1986-09-02 US claimed
EP-0168773-A2 Polymerizable 3-aroyloxyphenyl carbamates and methods for their preparation and use GENERAL ELECTRIC COMPANY (US) 1986-01-22 EP claimed
US-4520074-A SURFACE COATINGS FOR RESINOUS ARTICLES GENERAL ELECTRIC COMPANY (US) 1985-05-28 US claimed
US-4474855-A NONTOXIC E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-02 US claimed
US-4446175-A ACRYLATE, CHAIN TRANSFER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-05-01 US claimed
EP-0104283-A1 Dispersants for coating compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-04-04 EP claimed
US-4436885-A Preparation of isocyanate-functional polymers containing a terminal monosulfide group E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-03-13 US claimed
US-4369232-A POLYMERS OF ISOCYANATE ACRYLATES MODIFIED BY A FATTY AMINE AND ALKYL- OR ALKANOLAMINC; PAINTS; ENAMELS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-01-18 US claimed
US-4351755-A MOISTURE CURABLE COATINGS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-09-28 US claimed
US-4222909-A Coating compositions comprising isocyanate-functional polymers containing a terminal thioalkyl group E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-09-16 US claimed