SCHEMBL72966

SCHEMBL72966

C=C(C)C(=O)OCC=CN=C=O

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
THRB P10828 1/20 0.38
ALDH1A1 P00352 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10597585 0.84 TSHR (0.39) TSHRTHRBALDH1A1
SCHEMBL1636583 0.80 TSHR (0.52) TSHRTHRBALDH1A1
SCHEMBL1636584 0.80 TSHR (0.52) TSHRTHRBALDH1A1
SCHEMBL5654625 0.80 TSHR (0.52) TSHRTHRBALDH1A1
SCHEMBL78844 0.76 TSHR (0.39) TSHRTHRBALDH1A1
SCHEMBL169727 0.76 TSHR (0.44) TSHRTHRBALDH1A1
SCHEMBL11633090 0.76 ALOX15 (0.38)
SCHEMBL11221970 0.75 TSHR (0.40) TSHRTHRBALDH1A1
SCHEMBL453100 0.75 TSHR (0.47) TSHRTHRBALDH1A1
SCHEMBL10606524 0.75 TSHR (0.47) TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3283549-B1 POLYGLYCEROL DERIVATIVE AND A METHOD FOR MANUFACTURING THE SAME UNIV BERLIN FREIE (DE) 2019-07-17 EP claimed
US-20180092982-A1 POLYGLYCEROL DERIVATIVE AND A METHOD FOR MANUFACTURING THE SAME FREIE UNIVERSITÄT BERLIN (DE) 2018-04-05 US claimed
EP-3283549-A1 POLYGLYCEROL DERIVATIVE AND A METHOD FOR MANUFACTURING THE SAME Freie Universität Berlin (DE) 2018-02-21 EP claimed
WO-2016166317-A1 POLYGLYCEROL DERIVATIVE AND A METHOD FOR MANUFACTURING THE SAME FREIE UNIVERSITÄT BERLIN (DE) 2016-10-20 WO claimed
EP-2100907-B1 RESIN COMPOSITION FOR PRINTING PLATE ASAHI KASEI E MATERIALS CORP (JP) 2013-02-20 EP claimed
US-8129494-B2 Resin composition for printing plate ASAHI KASEI E-MATERIALS CORPORATION (JP) 2012-03-06 US claimed
US-20100093119-A1 RESIN COMPOSITION FOR PRINTING PLATE ASAHI KASEI E-MATERIALS CORPORATION (JP) 2010-04-15 US claimed
EP-2100907-A1 RESIN COMPOSITION FOR PRINTING PLATE Asahi Kasei Chemicals Corporation (JP) 2009-09-16 EP claimed
US-6245935-B1 TREATING ISOCYANATOALKYL (METH)ACRYLATE CONTAINING A HYDROLYZABLE CHLORIDE WITH AN EPOXY GROUP-CONTAINING COMPOUND AND AN AMINE AND/OR AN IMIDAZOLE TO REDUCE CONTENT OF HYDROLYZABLE CHLORIDE IN ISOCYANATOALKYL (METH)ACRYLATE SHOWA DENKO KABUSHIKI KAISHA (JP) 2001-06-12 US claimed
EP-1043605-A1 Extended wear ophthalmic lens Novartis AG (CH) 2000-10-11 EP claimed
US-5030696-A Air- or heat-curable protective coatings of unsaturated isocyanate-modified styrene-allyl alcohol copolymer, an acrylic compound and an allyl compound; furniture; toughness MONSANTO COMPANY (US) 1991-07-09 US claimed
EP-0104283-B1 DISPERSANTS FOR COATING COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-04-29 EP claimed
EP-0203361-A2 Improved polyester resin gelkote composition THE GLIDDEN COMPANY (formerly known as ATKEMIX EIGHT INC.) (US) 1986-12-03 EP claimed
US-4609706-A OXIDATIVELY CURABLE SCM CORPORATION (US) 1986-09-02 US claimed
US-4474855-A NONTOXIC E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-02 US claimed
US-4446175-A ACRYLATE, CHAIN TRANSFER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-05-01 US claimed
EP-0104283-A1 Dispersants for coating compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-04-04 EP claimed
US-4369232-A POLYMERS OF ISOCYANATE ACRYLATES MODIFIED BY A FATTY AMINE AND ALKYL- OR ALKANOLAMINC; PAINTS; ENAMELS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-01-18 US claimed
US-4351755-A MOISTURE CURABLE COATINGS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-09-28 US claimed
US-4222909-A Coating compositions comprising isocyanate-functional polymers containing a terminal thioalkyl group E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-09-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180092982-A1 POLYGLYCEROL DERIVATIVE AND A METHOD FOR MANUFACTURING THE SAME PHOSPHO1, DDOST, PPIP5K2 TSHR 2813/4885THRB 3556/4885ALDH1A1 4778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.