Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1575935 | 0.83 | HSD11B1 (0.44) | HSD11B1CMA1PRNPRXFP1ALDH1A1 | |
| SCHEMBL787663 | 0.81 | HSD11B1 (0.43) | HSD11B1CMA1PRNPRXFP1ALDH1A1 | |
| SCHEMBL9386310 | 0.79 | PFKFB3 (0.48) | HSD11B1CMA1PRNPRXFP1ALDH1A1 | |
| SCHEMBL7116533 | 0.78 | MCL1 (0.51) | RXFP1ALDH1A1GPR3POLBMAPT | |
| SCHEMBL1260291 | 0.77 | PFKFB3 (0.47) | HSD11B1CMA1PRNPRXFP1ALDH1A1 | |
| SCHEMBL4658351 | 0.76 | NPSR1 (0.47) | CMA1RXFP1PFKFB3L3MBTL1MCL1 | |
| SCHEMBL2226181 | 0.76 | NPSR1 (0.60) | CMA1PFKFB3MAPTL3MBTL1 | |
| SCHEMBL3946161 | 0.76 | PFKFB3 (0.53) | CMA1PFKFB3L3MBTL1 | |
| SCHEMBL787942 | 0.76 | CMA1 (0.51) | CMA1PFKFB3L3MBTL1 | |
| Hydrochloric Acid SCHEMBL6712744 | 0.75 | NPSR1 (0.59) | CMA1PFKFB3MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5232723-A | — | — | None | — | — | JP | disclosed |
| JP-2153576-A | — | — | None | — | — | JP | disclosed |
| EP-2616450-B1 | SULFONAMIDE COMPOUNDS | KANCERA AB (SE) | 2018-05-02 | — | — | EP | disclosed |
| EP-2616450-B1 | SULFONAMIDE COMPOUNDS | KANCERA AB (SE) | 2018-05-02 | — | — | EP | disclosed |
| US-9233946-B2 | Sulfonamide compounds | KANCERA AB (SE) | 2016-01-12 | — | — | US | disclosed |
| US-9233946-B2 | Sulfonamide compounds | KANCERA AB (SE) | 2016-01-12 | — | — | US | disclosed |
| US-9233946-B2 | Sulfonamide compounds | KANCERA AB (SE) | 2016-01-12 | — | — | US | disclosed |
| US-9198902-B2 | 1,4-dihydropyridine-3,5-dicarboxylate derivatives and preparation and use thereof | Xuanzhu Pharma Co., Ltd. (CN) | 2015-12-01 | — | — | US | disclosed |
| EP-2703398-A1 | 1,4-DIHYDROPYRIDINE -3,5-DICARBOXYLATE DERIVATIVES, PREPARATION METHODS AND USES THEREOF | Xuanzhu Pharma Co., Ltd. (CN) | 2014-03-05 | — | — | EP | disclosed |
| US-20140045896-A1 | 1,4-dihydropyridine-3,5-dicarboxylate Derivatives And Preparation And Use Thereof | Xuanzhu Pharma Co., Ltd. (CN) | 2014-02-13 | — | — | US | disclosed |
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| EP-2137152-A1 | NOVEL BENZAMIDE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Dong-A Pharm.Co., Ltd. (KR) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008114971-A1 | NOVEL BENZAMIDE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | DONG-A PHARM. CO., LTD. (KR) | 2008-09-25 | — | — | WO | disclosed |
| EP-1597248-B1 | SULFONAMIDE DERIVATIVES AS PPAR MODULATORS | LILLY CO ELI (US) | 2007-12-26 | — | — | EP | disclosed |
| US-20060217433-A1 | Sulfonamide derivatives as ppar modulators | ELI LILLY AND COMPANY (US) | 2006-09-28 | — | — | US | disclosed |
| EP-1597248-A2 | SULFONAMIDE DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004073606-A2 | SULFONAMIDE DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-09-02 | — | — | WO | disclosed |
| JP-H05232723-A | ELECTROPHOTOGRAPHIC SENSITIVE MEMBER | KONICA CORP | 1993-09-10 | — | — | JP | disclosed |
| JP-H02153576-A | PHOTOELECTRIC CONVERSION ELEMENT | RICOH CO LTD | 1990-06-13 | — | — | JP | disclosed |
| US-3979180-A | PHENOL, DIPHENYLAMINE, THIOPHOSPHATES, TRANSITION METAL | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1976-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140045896-A1 | 1,4-dihydropyridine-3,5-dicarboxylate Derivatives And Preparation And Use Thereof | PKD1, REN, GLS | HSD11B1 3333/4885CMA1 1915/4885PRNP 3927/4885 |
| US-20060217433-A1 | Sulfonamide derivatives as ppar modulators | PPARD, PPARA, PPARG | HSD11B1 92/4885CMA1 4529/4885PRNP 4349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.