Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7892210 | 0.81 | ALDH1A1 (0.52) | ALOX15HPGDMEN1KMT2ATSHR | |
| SCHEMBL7894602 | 0.78 | ALDH1A1 (0.51) | ALOX15HPGDMEN1KMT2ATSHR | |
| SCHEMBL7896107 | 0.77 | MAPT (0.48) | ALOX15HPGDMEN1KMT2ATSHR | |
| SCHEMBL7892188 | 0.77 | ALDH1A1 (0.53) | ALOX15HPGDMEN1KMT2ATSHR | |
| SCHEMBL1790108 | 0.75 | MAPT (0.56) | ALOX15HPGDMEN1KMT2ATSHR | |
| SCHEMBL1788479 | 0.75 | ALDH1A1 (0.59) | ALOX15HPGDMEN1KMT2ANPSR1 | |
| SCHEMBL1786996 | 0.75 | MEN1 (0.48) | ALOX15HPGDMEN1KMT2ATSHR | |
| SCHEMBL30794643 | 0.75 | MAPT (0.56) | ALOX15HPGDMEN1KMT2ATSHR | |
| SCHEMBL30795705 | 0.75 | ALDH1A1 (0.59) | ALOX15HPGDMEN1KMT2ANPSR1 | |
| SCHEMBL30795813 | 0.75 | MEN1 (0.48) | ALOX15HPGDMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180629-B1 | INDUCING OR PROMOTING APOPTOSIS AND FOR ARRESTING UNCONTROLLED NEOPLASTIC CELL PROLIFERATION, INCLUDING PRECANCEROUS AND CANCEROUS LESIONS | CELL PATHWAYS, INC. | 2001-01-30 | — | — | US | disclosed |