Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7894602 | 0.86 | ALDH1A1 (0.51) | ALDH1A1ALOX15MEN1KMT2ATSHR | |
| SCHEMBL7885140 | 0.81 | ALOX15 (0.54) | ALDH1A1ALOX15ADORA3MEN1KMT2A | |
| SCHEMBL7892188 | 0.80 | ALDH1A1 (0.53) | ALDH1A1ALOX15MEN1KMT2ATSHR | |
| SCHEMBL7893043 | 0.77 | KMT2A (0.73) | ALDH1A1ALOX15MEN1KMT2ATSHR | |
| SCHEMBL30796074 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2APOLBLMNA | |
| SCHEMBL1789674 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2APOLBLMNA | |
| SCHEMBL1790108 | 0.76 | MAPT (0.56) | ALDH1A1ALOX15MEN1KMT2ATSHR | |
| SCHEMBL30794643 | 0.76 | MAPT (0.56) | ALDH1A1ALOX15MEN1KMT2ATSHR | |
| SCHEMBL30795705 | 0.76 | ALDH1A1 (0.59) | ALDH1A1ALOX15MEN1KMT2ALMNA | |
| SCHEMBL1788479 | 0.76 | ALDH1A1 (0.59) | ALDH1A1ALOX15MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180629-B1 | INDUCING OR PROMOTING APOPTOSIS AND FOR ARRESTING UNCONTROLLED NEOPLASTIC CELL PROLIFERATION, INCLUDING PRECANCEROUS AND CANCEROUS LESIONS | CELL PATHWAYS, INC. | 2001-01-30 | — | — | US | disclosed |