Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7892197 | 0.87 | LIPG (0.42) | ALDH1A1ALOX15ALOX12HPGDMEN1 | |
| SCHEMBL7892210 | 0.86 | ALDH1A1 (0.52) | ALDH1A1ALOX15HPGDMEN1KMT2A | |
| SCHEMBL7896107 | 0.82 | MAPT (0.48) | ALDH1A1ALOX15HPGDMEN1KMT2A | |
| SCHEMBL7885140 | 0.78 | ALOX15 (0.54) | ALDH1A1ALOX15HPGDMEN1KMT2A | |
| SCHEMBL7892188 | 0.77 | ALDH1A1 (0.53) | ALDH1A1ALOX15HPGDMEN1KMT2A | |
| SCHEMBL7893043 | 0.73 | KMT2A (0.73) | ALDH1A1ALOX15HPGDMEN1KMT2A | |
| SCHEMBL1788479 | 0.72 | ALDH1A1 (0.59) | ALDH1A1ALOX15HPGDMEN1KMT2A | |
| SCHEMBL30796074 | 0.72 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL30794643 | 0.72 | MAPT (0.56) | ALDH1A1ALOX15HPGDMEN1KMT2A | |
| SCHEMBL30795705 | 0.72 | ALDH1A1 (0.59) | ALDH1A1ALOX15HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180629-B1 | INDUCING OR PROMOTING APOPTOSIS AND FOR ARRESTING UNCONTROLLED NEOPLASTIC CELL PROLIFERATION, INCLUDING PRECANCEROUS AND CANCEROUS LESIONS | CELL PATHWAYS, INC. | 2001-01-30 | — | — | US | disclosed |