Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7883247 | 0.91 | DGAT1 (0.71) | DGAT1MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7889341 | 0.90 | DGAT1 (0.62) | DGAT1MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7889343 | 0.90 | DGAT1 (0.62) | DGAT1MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL13114778 | 0.87 | DGAT1 (0.53) | DGAT1MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7878324 | 0.81 | DGAT1 (0.59) | DGAT1MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7886309 | 0.81 | DGAT1 (0.74) | DGAT1MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL13114760 | 0.81 | DGAT1 (0.59) | DGAT1MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8931187 | 0.80 | MAPT (0.44) | MAPTLMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL8931127 | 0.79 | DGAT1 (0.72) | DGAT1MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL17249818 | 0.78 | DGAT1 (0.69) | DGAT1MAPTLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754180-B1 | ANTI-HELICOBACTER ESTER AND CARBAMATE DERIVATIVES OF AZOLONES | JANSSEN PHARMACEUTICA NV (BE) | 2001-10-31 | — | — | EP | claimed |
| EP-0754180-A1 | ANTI-HELICOBACTER ESTER AND CARBAMATE DERIVATIVES OF AZOLONES | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-01-22 | — | — | EP | claimed |
| WO-1995027704-A1 | ANTI-HELICOBACTER ESTER AND CARBAMATE DERIVATIVES OF AZOLONES | JANSSEN PHARMACEUTICA N.V. (BE) | 1995-10-19 | — | — | WO | claimed |
| EP-0754180-B1 | ANTI-HELICOBACTER ESTER AND CARBAMATE DERIVATIVES OF AZOLONES | JANSSEN PHARMACEUTICA NV (BE) | 2001-10-31 | — | — | EP | disclosed |