Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931193 | 0.91 | DGAT1 (0.47) | MAPTLMNAGAAKDM4EMEN1 | |
| SCHEMBL8931190 | 0.82 | SMN1; SMN2 (0.43) | MAPTLMNAGAAKDM4EALDH1A1 | |
| SCHEMBL13114778 | 0.81 | DGAT1 (0.53) | MAPTLMNAGAAKDM4EMEN1 | |
| SCHEMBL7885192 | 0.80 | DGAT1 (0.59) | MAPTLMNAGAAKDM4EMEN1 | |
| SCHEMBL8931128 | 0.78 | AKR1C3 (0.48) | MAPTLMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL13114808 | 0.77 | MAPT (0.60) | MAPTLMNAGAAKDM4EMEN1 | |
| SCHEMBL7331958 | 0.75 | MAPT (0.46) | MAPTLMNAGAAKDM4EMEN1 | |
| SCHEMBL13114760 | 0.74 | DGAT1 (0.59) | MAPTLMNAGAAKDM4EALDH1A1 | |
| SCHEMBL9275050 | 0.73 | HTR1A (0.40) | MAPTLMNAGAAKDM4EALDH1A1 | |
| SCHEMBL9274889 | 0.71 | MAPT (0.43) | MAPTLMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754180-A1 | ANTI-HELICOBACTER ESTER AND CARBAMATE DERIVATIVES OF AZOLONES | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-01-22 | — | — | EP | claimed |
| WO-1995027704-A1 | ANTI-HELICOBACTER ESTER AND CARBAMATE DERIVATIVES OF AZOLONES | JANSSEN PHARMACEUTICA N.V. (BE) | 1995-10-19 | — | — | WO | claimed |