Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 9/20 | 0.51 |
| ▸ | CASP7 | P55210 | 4/20 | 0.51 |
| ▸ | CASP1 | P29466 | 4/20 | 0.51 |
| ▸ | CASP9 | P55211 | 3/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CASP4 | P49662 | 1/20 | 0.45 |
| ▸ | CASP5 | P51878 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.45 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7877652 | 0.83 | CASP1 (0.51) | CASP3CASP1CASP9SMN1; SMN2SIRT5 | |
| SCHEMBL18781744 | 0.79 | CASP3 (0.74) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL9961887 | 0.79 | CASP3 (0.74) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL18472372 | 0.79 | CASP3 (0.74) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL20052444 | 0.78 | CASP3 (0.60) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL3490062 | 0.78 | CASP3 (0.54) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL15462717 | 0.78 | CASP3 (0.76) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL15462667 | 0.77 | CASP3 (0.67) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL15462718 | 0.77 | CASP3 (0.63) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL16770334 | 0.76 | CASP3 (0.68) | CASP3CASP7CASP1CASP9CASP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010133000-A1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | NEW WORLD LABORATORIES INC. (CA) | 2010-11-25 | — | — | WO | disclosed |