Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 14/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9962572 | 0.91 | CYP2D6 (0.44) | CYP2D6CTSKCA2CA1CA7 | |
| SCHEMBL7879286 | 0.79 | CYP1A2 (0.40) | CYP2D6CA2CA12CA14CYP1A2 | |
| SCHEMBL13471117 | 0.78 | CYP2D6 (0.45) | CYP2D6CTSKCYP1A2CYP2C19 | |
| SCHEMBL7885775 | 0.77 | CTSK (0.49) | CYP2D6CTSKCA2CA1CA7 | |
| SCHEMBL3498624 | 0.76 | CTSK (0.62) | CYP2D6CTSKCA2CA1CA7 | |
| SCHEMBL28907829 | 0.76 | CTSK (0.62) | CYP2D6CTSKCA2CA1CA7 | |
| SCHEMBL1261148 | 0.76 | CTSK (0.62) | CYP2D6CTSKCA2CA1CA7 | |
| SCHEMBL19015874 | 0.76 | CYP2D6 (0.48) | CYP2D6CTSKCA2CA1CA7 | |
| SCHEMBL271514 | 0.75 | CTSK (0.60) | CYP2D6CTSKCA2CA12CA14 | |
| SCHEMBL271513 | 0.75 | CTSK (0.60) | CYP2D6CTSKCA2CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975119-B2 | Selective cysteine protease inhibitors and uses thereof | GENESIS TECHNOLOGIES LIMITED (BB) | 2021-04-13 | — | — | US | disclosed |
| US-20180186833-A1 | SELECTIVE CYSTEINE PROTEASE INHIBITORS AND USES THEREOF | GENESIS TECH LIMITED (BB) | 2018-07-05 | — | — | US | disclosed |
| US-20180186833-A1 | SELECTIVE CYSTEINE PROTEASE INHIBITORS AND USES THEREOF | GENESIS TECH LIMITED (BB) | 2018-07-05 | — | — | US | disclosed |
| US-9944674-B2 | Selective cysteine protease inhibitors and uses thereof | GENESIS TECHNOLOGIES LIMITED (BB) | 2018-04-17 | — | — | US | disclosed |
| US-9944674-B2 | Selective cysteine protease inhibitors and uses thereof | GENESIS TECHNOLOGIES LIMITED (BB) | 2018-04-17 | — | — | US | disclosed |
| US-9045524-B2 | Selective caspase inhibitors and uses thereof | NOVAGENESIS FOUNDATION (CH) | 2015-06-02 | — | — | US | disclosed |
| US-9045524-B2 | Selective caspase inhibitors and uses thereof | NOVAGENESIS FOUNDATION (CH) | 2015-06-02 | — | — | US | disclosed |
| US-20140038903-A1 | Selective Cysteine Protease Inhibitors and Uses Thereof | NEW WORLD LABORATORIES, INC. (CA) | 2014-02-06 | — | — | US | disclosed |
| US-20140038903-A1 | Selective Cysteine Protease Inhibitors and Uses Thereof | NEW WORLD LABORATORIES, INC. (CA) | 2014-02-06 | — | — | US | disclosed |
| US-20120157394-A1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | NEW WORLD LABORATORIES, INC. (CA) | 2012-06-21 | — | — | US | disclosed |
| WO-2010133000-A1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | NEW WORLD LABORATORIES INC. (CA) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157394-A1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | CASP1, VIP, CASP5 | CYP2D6 1664/4885CTSK 90/4885CA2 788/4885 |
| US-20140038903-A1 | Selective Cysteine Protease Inhibitors and Uses Thereof | SERPINB1, SERPINE1, CASP5 | CYP2D6 1585/4885CTSK 138/4885CA2 1932/4885 |
| US-20180186833-A1 | SELECTIVE CYSTEINE PROTEASE INHIBITORS AND USES THEREOF | SERPINB1, SERPINE1, CASP5 | CYP2D6 1585/4885CTSK 138/4885CA2 1932/4885 |
| US-10975119-B2 | Selective cysteine protease inhibitors and uses thereof | SERPINB1, SERPINE1, CASP5 | CYP2D6 1568/4885CTSK 128/4885CA2 1968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.