SCHEMBL788852

SCHEMBL788852

Oc1ccc2c(c1)Cc1cc(O)ccc1-2

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 1/20 0.64
ESR1 P03372 8/20 0.55
ESR2 Q92731 8/20 0.55
DRD2 P14416 4/20 0.54
DRD1 P21728 4/20 0.54
DRD5 P21918 3/20 0.54
DRD3 P35462 3/20 0.54
MAOA P21397 2/20 0.48
MAOB P27338 2/20 0.48
PRKCI P41743 1/20 0.48
CYP17A1 P05093 1/20 0.47
CYP19A1 P11511 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA4 P22748 1/20 0.47
CA6 P23280 1/20 0.47
DRD4 P21917 1/20 0.47
PBRM1 Q86U86 1/20 0.46
NPC1 O15118 1/20 0.46
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29439100 1.00 HSD17B1 (0.64) HSD17B1ESR1ESR2DRD2DRD1
SCHEMBL217399 0.89 KDM4E (0.59) HSD17B1ESR1ESR2DRD2DRD1
SCHEMBL29373696 0.89 KDM4E (0.59) HSD17B1ESR1ESR2DRD2DRD1
SCHEMBL24727048 0.87 ESR1 (0.56) HSD17B1ESR1ESR2DRD2DRD1
SCHEMBL6536288 0.87 HSD17B1 (0.53) HSD17B1ESR1ESR2DRD2DRD1
SCHEMBL15869784 0.87 HSD17B1 (0.58) HSD17B1ESR1ESR2DRD2DRD1
SCHEMBL21318766 0.86
SCHEMBL30672580 0.86
SCHEMBL14317167 0.86 DRD1 (0.61) HSD17B1ESR1ESR2DRD2DRD1
SCHEMBL784291 0.83 MAOB (0.59) HSD17B1ESR1ESR2DRD2MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024221958-A1 PREPARATION METHOD FOR MODIFIED POLYETHERSULFONE/POLYETHERIMIDE POLYMER ALLOY 深圳先进技术研究院 2024-10-31 WO claimed
CN-116675861-A Preparation method of modified polyethersulfone/polyetherimide polymer alloy 深圳先进技术研究院 2023-09-01 CN claimed
CN-114316232-B Polyester resin for high-hardness high-transparency powder coating and preparation method thereof 广东腐蚀科学与技术创新研究院 2023-04-14 CN claimed
CN-115819712-A Low-dielectric-property thermoplastic polyurethane elastomer, and preparation method and application thereof 万华化学集团股份有限公司 2023-03-21 CN claimed
CN-114316232-A Polyester resin for high-hardness high-transparency powder coating and preparation method thereof 广东腐蚀科学与技术创新研究院 2022-04-12 CN claimed
CN-109721701-B Thermoplastic polyurethane elastomer composition, preparation method and application thereof 万华化学集团股份有限公司 2021-09-03 CN claimed
US-12583973-B2 Polyimide-based polymer, positive photosensitive resin composition, negative photosensitive resin composition, patterning method, method for forming cured film, interlayer insulating film, surface protective film, and electronic component SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-03-24 US disclosed
WO-2024221958-A1 PREPARATION METHOD FOR MODIFIED POLYETHERSULFONE/POLYETHERIMIDE POLYMER ALLOY 深圳先进技术研究院 2024-10-31 WO disclosed
CN-115044040-B Polyimide-containing polymer, positive photosensitive resin composition, negative photosensitive resin composition, and pattern forming method 信越化学工业株式会社 2024-07-02 CN disclosed
CN-114206990-B Fiber-reinforced polyarylene sulfide copolymer composite substrate, method for producing same, and molded article containing same 东丽株式会社 2024-06-21 CN disclosed
CN-113816854-B Polymerizable compound based on 2, 7-dihydroxyfluorene and preparation method and application thereof 江苏创拓新材料有限公司 2024-06-18 CN disclosed
CN-113816854-B Polymerizable compound based on 2, 7-dihydroxyfluorene and preparation method and application thereof 江苏创拓新材料有限公司 2024-06-18 CN disclosed
CN-115989267-B Method for producing polyarylene sulfide, method for producing polyarylene sulfide copolymer, and polyarylene sulfide 东丽株式会社 2024-03-29 CN disclosed
US-4217407-A Light-sensitive O-quinone diazide containing copying material FUJI PHOTO FILM CO., LTD. (JP) 1980-08-12 US disclosed
US-4207106-A Positive working O-quinone diazide photocopying process with organic resin overlayer FUJI PHOTO FILM CO., LTD. (JP) 1980-06-10 US disclosed
US-4197128-A Light-sensitive O-quinone diazide containing copying material FUJI PHOTO FILM CO., LTD. (JP) 1980-04-08 US disclosed
US-4191573-A O-QUINONE DIAZIDE, AN ALKALI-SOLUBLE ARYL AZIDE, A POLYAMIDE FUJI PHOTO FILM CO., LTD. (JP) 1980-03-04 US disclosed
US-4041165-A TREATING DELAYED HYPERSENSITIVITY RICHARDSON-MERRELL INC. (US) 1977-08-09 US disclosed
US-3947593-A ANTIVIRUL AGENTS RICHARDSON-MERRELL INC. (US) 1976-03-30 US disclosed
US-3937833-A DELAYED HYPERSENSITIVITY RICHARDSON-MERRELL INC. (US) 1976-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583973-B2 Polyimide-based polymer, positive photosensitive resin composition, negative photosensitive resin composition, patterning method, method for forming cured film, interlayer insulating film, surface protective film, and electronic component PRDM9, ARCN1, PUF60 HSD17B1 3966/4885ESR1 119/4885ESR2 436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.