Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | ROS1 | P08922 | 1/20 | 0.43 |
| ▸ | MARK3 | P27448 | 1/20 | 0.43 |
| ▸ | LTK | P29376 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31268298 | 0.88 | SRD5A1 (0.58) | HSD17B1MAOAMAOBSRD5A1SRD5A2 | |
| SCHEMBL23036050 | 0.88 | SRD5A1 (0.58) | HSD17B1MAOAMAOBSRD5A1SRD5A2 | |
| SCHEMBL28126153 | 0.87 | METAP1 (0.57) | METAP1TDP2SRD5A1SRD5A2CHEK2 | |
| SCHEMBL29376113 | 0.87 | METAP1 (0.57) | METAP1TDP2SRD5A1SRD5A2CHEK2 | |
| SCHEMBL788852 | 0.87 | HSD17B1 (0.64) | HSD17B1MAOAMAOBESR1ESR2 | |
| SCHEMBL29439100 | 0.87 | HSD17B1 (0.64) | HSD17B1MAOAMAOBESR1ESR2 | |
| SCHEMBL40823 | 0.87 | METAP1 (0.57) | METAP1TDP2SRD5A1SRD5A2CHEK2 | |
| SCHEMBL3129344 | 0.85 | METAP1 (0.52) | METAP1TDP2SRD5A1SRD5A2CHEK2 | |
| SCHEMBL28360994 | 0.85 | METAP1 (0.52) | METAP1TDP2SRD5A1SRD5A2CHEK2 | |
| SCHEMBL29569917 | 0.85 | METAP1 (0.52) | METAP1TDP2SRD5A1SRD5A2CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6824709-B2 | A LIQUID CRYSTAL COMPOUND OR LIQUID CRYSTAL POLYMERS, CONTAINING ACRYLATE OR METHACRYLATE FLUORENE GROUP; LIQUID CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20030203128-A1 | Fluorene derivatives and their polymers | JNC PETROCHEMICAL CORPORATION (JP) | 2003-10-30 | — | — | US | disclosed |
| US-4545921-A | Liquid crystals having a type A smectic phase | THOMSON-CSF (FR) | 1985-10-08 | — | — | US | disclosed |