Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77529 | 0.83 | ALDH1A1 (0.37) | PARP10PARP1MAOBALDH1A1TYMS | |
| SCHEMBL79135 | 0.79 | BRD4 (0.43) | TDP1CYP3A4PARP1MAOBMAOA | |
| SCHEMBL78707 | 0.73 | MAPK14 (0.36) | PARP10PARP1MAOBALDH1A1HSD17B10 | |
| SCHEMBL30092409 | 0.72 | TDP1 (0.65) | TDP1CYP3A4ALOX15TP53THRB | |
| SCHEMBL18131295 | 0.72 | TDP1 (0.65) | TDP1CYP3A4ALOX15TP53THRB | |
| SCHEMBL29900990 | 0.72 | TDP1 (0.65) | TDP1CYP3A4ALOX15TP53THRB | |
| Hydrochloric Acid SCHEMBL29900992 | 0.70 | TDP1 (0.62) | TDP1CYP3A4ALOX15TP53THRB | |
| SCHEMBL11304327 | 0.70 | CYP2D6 (0.47) | TDP1ALOX15ALDH1A1HSD17B10ACHE | |
| SCHEMBL77967 | 0.69 | LMNA (0.51) | TDP1CYP3A4ALDH1A1LMNACA1 | |
| SCHEMBL8733733 | 0.69 | MAOB (0.52) | SMN1; SMN2PARP10PARP1MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129488-B2 | Transition metal complexes, catalyst compositions containing the same, and olefin polymerization using the catalyst compositions | LG CHEM, LTD. (KR) | 2012-03-06 | — | — | US | disclosed |
| US-20090209712-A1 | TRANSITION METAL COMPLEXES, CATALYST COMPOSITIONS CONTAINING THE SAME, AND OLEFIN POLYMERIZATION USING THE CATALYST COMPOSITIONS | LG CHEM., LTD. (KR) | 2009-08-20 | — | — | US | disclosed |
| US-7538239-B2 | Transition metal complexes, catalyst compositions containing the same, and olefin polymerization using the catalyst compositions | LG CHEM, LTD. (KR) | 2009-05-26 | — | — | US | disclosed |
| WO-2007007992-A1 | TRANSITION METAL COMPLEXES, CATALYST COMPOSITIONS CONTAINING THE SAME, AND OLEFIN POLYMERIZATION USING THE CATALYST COMPOSITIONS | LG CHEM, LTD. (KR) | 2007-01-18 | — | — | WO | disclosed |
| US-20070010637-A1 | Transition metal complexes, catalyst compositions containing the same, and olefin polymerization using the catalyst compositions | LG CHEM, LTD. (KR) | 2007-01-11 | — | — | US | disclosed |