SCHEMBL788916

SCHEMBL788916

CC(C)Cc1ccc2[nH]c3ccc(-c4cccc5c4oc4ccccc45)cc3c2c1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.48
GGPS1 O95749 1/20 0.42
PRKDC P78527 2/20 0.37
PTGES2 Q9H7Z7 1/20 0.35
PRMT5 O14744 1/20 0.35
WDR77 Q9BQA1 1/20 0.35
ECE1 P42892 2/20 0.33
C3AR1 Q16581 1/20 0.33
TLR8 Q9NR97 2/20 0.32
TLR7 Q9NYK1 2/20 0.32
NPY5R Q15761 1/20 0.32
MMP12 P39900 1/20 0.32
MMP13 P45452 1/20 0.32
HSP90AA1 P07900 1/20 0.32
HSP90AB1 P08238 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL768872 0.86 ALOX5 (0.62) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL789001 0.85 ALOX5 (0.49) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL18381878 0.84 ALOX5 (0.61) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL789004 0.83 ALOX5 (0.47) ALOX5GGPS1PRKDCCYP1A2CYP2D6
SCHEMBL457912 0.83 ALOX5 (0.59) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL30395989 0.83 ALOX5 (0.59) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL30487044 0.83 ALOX5 (0.59) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL788722 0.83 ALOX5 (0.51) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL18381837 0.82 ALOX5 (0.58) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL10227375 0.81 ALOX5 (0.36) ALOX5PRKDCTLR8TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 ALOX5 1162/4885GGPS1 2063/4885PRKDC 3567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.