SCHEMBL457912

SCHEMBL457912

c1ccc2c(c1)[nH]c1ccc(-c3cccc4c3oc3ccccc34)cc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.59
GGPS1 O95749 1/20 0.44
PRKDC P78527 4/20 0.44
AHR P35869 2/20 0.43
KIF11 P52732 4/20 0.42
PTGES2 Q9H7Z7 1/20 0.41
ALDH1A1 P00352 2/20 0.40
HSD17B10 Q99714 2/20 0.40
GPR3 P46089 1/20 0.40
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
KMT2A Q03164 1/20 0.39
ATM Q13315 1/20 0.37
PRMT5 O14744 1/20 0.36
WDR77 Q9BQA1 1/20 0.36
CASP3 P42574 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30395989 1.00 ALOX5 (0.59) ALOX5GGPS1PRKDCAHRKIF11
SCHEMBL30487044 1.00 ALOX5 (0.59) ALOX5GGPS1PRKDCAHRKIF11
SCHEMBL18381837 0.99 ALOX5 (0.58) ALOX5GGPS1PRKDCAHRKIF11
SCHEMBL768872 0.97 ALOX5 (0.62) ALOX5GGPS1PRKDCAHRKIF11
SCHEMBL15790770 0.96 ALOX5 (0.56) ALOX5GGPS1PRKDCAHRKIF11
SCHEMBL17319567 0.96 ALOX5 (0.56) ALOX5GGPS1PRKDCAHRKIF11
SCHEMBL18381878 0.96 ALOX5 (0.61) ALOX5GGPS1PRKDCAHRKIF11
SCHEMBL17885209 0.94 ALOX5 (0.53) ALOX5GGPS1PRKDCAHRKIF11
SCHEMBL788745 0.92 ALOX5 (0.57) ALOX5GGPS1PRKDCPTGES2KDM4E
SCHEMBL788870 0.92 ALOX5 (0.57) ALOX5GGPS1PRKDCPTGES2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230371368-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-16 US disclosed
WO-2023213837-A1 CYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-11-09 WO disclosed
US-20230232714-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-20 US disclosed
US-20230232714-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-20 US disclosed
WO-2023082808-A1 TETRAAZA-FLUORANTHENE COMPOUND AND APPLICATION THEREOF 上海八亿时空先进材料有限公司 2023-05-19 WO disclosed
WO-2023052272-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-04-06 WO disclosed
EP-3679024-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2022-11-02 EP disclosed
EP-3679023-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2022-11-02 EP disclosed
EP-3237409-B1 CARBAZOLES WITH TWO DIBENZOFURAN OR DIBENZOTHIOPHENE SUBSTITUENTS MERCK PATENT GMBH (DE) 2022-01-05 EP disclosed
EP-3237409-B1 CARBAZOLES WITH TWO DIBENZOFURAN OR DIBENZOTHIOPHENE SUBSTITUENTS MERCK PATENT GMBH (DE) 2022-01-05 EP disclosed
US-20120133274-A1 Carbazole Compound, Light-Emitting Element Material, Organic Semiconductor Material, Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-31 US disclosed
US-20120074390-A1 Light-Emitting Element and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-29 US disclosed
US-20120074390-A1 Light-Emitting Element and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-29 US disclosed
WO-2012039262-A1 CARBAZOLE DERIVATIVE, LIGHT-EMITTING ELEMENT MATERIAL AND ORGANIC SEMICONDUCTOR MATERIAL SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-29 WO disclosed
WO-2012039262-A1 CARBAZOLE DERIVATIVE, LIGHT-EMITTING ELEMENT MATERIAL AND ORGANIC SEMICONDUCTOR MATERIAL SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-29 WO disclosed
WO-2012036482-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2012-03-22 WO disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed
WO-2012033108-A1 LIGHT-EMITTING ELEMENT AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-15 WO disclosed
WO-2012033108-A1 LIGHT-EMITTING ELEMENT AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230232714-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME NFE2L2, CRY1, LAGE3 ALOX5 2212/4885GGPS1 748/4885PRKDC 3748/4885
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 ALOX5 1162/4885GGPS1 2063/4885PRKDC 3567/4885
US-20230371368-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SLC1A2, SLC18A1, SLC18A2 ALOX5 1208/4885GGPS1 3075/4885PRKDC 4083/4885
US-20120133274-A1 Carbazole Compound, Light-Emitting Element Material, Organic Semiconductor Material, Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device BRI3BP, BRD7, CDYL ALOX5 1378/4885GGPS1 2201/4885PRKDC 1839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.