Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429168 | 0.94 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1HTTHPGDHSD17B10 | |
| SCHEMBL7888362 | 0.90 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1HTTHPGDHSD17B10 | |
| SCHEMBL7423152 | 0.85 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1HTTHPGDHSD17B10 | |
| SCHEMBL8200310 | 0.84 | HPGD (0.56) | SMN1; SMN2ALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL7421896 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1HTTHPGDHSD17B10 | |
| SCHEMBL7890880 | 0.83 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1HTTHPGDHSD17B10 | |
| SCHEMBL8212886 | 0.77 | HPGD (0.58) | SMN1; SMN2ALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL7421905 | 0.73 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1HTTHPGDHSD17B10 | |
| SCHEMBL7886971 | 0.72 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL8207225 | 0.72 | HPGD (0.60) | SMN1; SMN2ALDH1A1HPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934301-B1 | AMINOTHIOPHENE CARBOXYLIC ACID AMIDES AND THE USE THEREOF AS PHOSPHODIESTERASE INHIBITORS | MERCK PATENT GMBH (DE) | 2001-06-20 | — | — | EP | disclosed |