SCHEMBL7889558

SCHEMBL7889558

O=C(OCO)C1CC2C=CC1C2

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
KDM4E B2RXH2 2/20 0.50
ALDH1A1 P00352 10/20 0.49
KMT2A Q03164 3/20 0.49
RAB9A P51151 1/20 0.49
POLB P06746 3/20 0.47
HSD17B10 Q99714 2/20 0.47
APEX1 P27695 1/20 0.47
RECQL P46063 1/20 0.47
BLM P54132 1/20 0.47
ESR2 Q92731 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
HPGD P15428 1/20 0.47
MAPK1 P28482 2/20 0.40
MAPT P10636 1/20 0.39
MEN1 O00255 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14213298 0.87 ALDH1A1 (0.53) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL10388301 0.87 ALDH1A1 (0.53) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL17192089 0.87 LMNA (0.52) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL13897067 0.87 ALDH1A1 (0.53) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL525277 0.86 LMNA (0.47) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL14531160 0.86 LMNA (0.47) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL2754655 0.84 ALDH1A1 (0.49) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL2754654 0.84 ALDH1A1 (0.49) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL8961484 0.84 LMNA (0.49) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL2774448 0.84 POLB (0.49) LMNAKDM4EALDH1A1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6180316-B1 SUITABLE FOR USE AS CHEMICALLY AMPLIFIED RESIST USED IN MANUFACTURING OF INTEGRATED CIRCUITS JSR CORPORATION (JP) 2001-01-30 US disclosed
EP-0930541-A1 Radiation sensitive resin composition JSR Corporation (JP) 1999-07-21 EP disclosed