Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11339113 | 0.86 | ALDH1A1 (0.46) | LMNAKDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL14213298 | 0.85 | ALDH1A1 (0.53) | LMNAKDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL10388301 | 0.85 | ALDH1A1 (0.53) | LMNAKDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL17192089 | 0.85 | LMNA (0.52) | LMNAKDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL13897067 | 0.85 | ALDH1A1 (0.53) | LMNAKDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL7889558 | 0.84 | LMNA (0.50) | LMNAKDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL2754655 | 0.82 | ALDH1A1 (0.49) | LMNAKDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL2754654 | 0.82 | ALDH1A1 (0.49) | LMNAKDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL19498813 | 0.82 | LMNA (0.49) | LMNAKDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL2774448 | 0.82 | POLB (0.49) | LMNAKDM4EALDH1A1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409291-B1 | Thermoplastic resin composition | JAPAN SYNTHETIC RUBBER CO LTD (JP) | 1996-02-14 | — | — | EP | disclosed |
| EP-0317262-B1 | Transparent resin material | JAPAN SYNTHETIC RUBBER CO LTD (JP) | 1996-01-31 | — | — | EP | disclosed |
| US-5164469-A | Substrate for optical disks, ring opening polymerization of tetracyclododecene derivatives | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1992-11-17 | — | — | US | disclosed |
| US-5053471-A | Methathesis ring opening polymerization of polar substituted norbornenes or octahydromethanonphthalenes; optics | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0409291-A2 | Thermoplastic resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-01-23 | — | — | EP | disclosed |
| EP-0317262-A2 | Transparent resin material | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1989-05-24 | — | — | EP | disclosed |