Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 10/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22402473 | 1.00 | ALDH1A1 (0.37) | ALDH1A1PKMHSD11B1OPRM1OPRL1 | |
| SCHEMBL788956 | 1.00 | ALDH1A1 (0.37) | ALDH1A1PKMHSD11B1OPRM1OPRL1 | |
| SCHEMBL788957 | 1.00 | ALDH1A1 (0.37) | ALDH1A1PKMHSD11B1OPRM1OPRL1 | |
| SCHEMBL789124 | 0.98 | ALDH1A1 (0.38) | ALDH1A1PKM | |
| SCHEMBL789272 | 0.98 | ALDH1A1 (0.38) | ALDH1A1PKM | |
| SCHEMBL9567813 | 0.98 | ALDH1A1 (0.38) | ALDH1A1PKM | |
| SCHEMBL10752789 | 0.98 | ALDH1A1 (0.38) | ALDH1A1PKM | |
| SCHEMBL789556 | 0.94 | ALDH1A1 (0.33) | ALDH1A1PKM | |
| SCHEMBL789484 | 0.94 | ALDH1A1 (0.33) | ALDH1A1PKM | |
| SCHEMBL16938253 | 0.94 | ALDH1A1 (0.33) | ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105832740-B | Aryl amine purine derivative and preparation method thereof and purposes in medicine | 石药集团中奇制药技术（石家庄）有限公司 | 2019-02-12 | — | — | CN | claimed |
| CN-103957883-B | Comprising by the pretreating agent for keratin fiber of the methyl substituted silicone of 4 morpholinyls | 汉高股份有限及两合公司 | 2017-06-23 | — | — | CN | claimed |
| CN-105832740-A | Aromatic amino purine derivative as well as preparation method and pharmaceutical application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2016-08-10 | — | — | CN | claimed |
| CN-102656180-B | As the feather fan alcohol type triterpene derivative of antiviral drug | HETERO RESEARCH FOUNDATION (IN) | 2016-04-20 | — | — | CN | claimed |
| CN-103003278-B | Arylamino purine derivatives, preparation method and medical application thereof | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) Co.,Ltd. (CN) | 2016-03-30 | — | — | CN | claimed |
| CN-105308036-A | Compounds and methods for kinase modulation, and indications therefor | PLEXXIKON INC | 2016-02-03 | — | — | CN | claimed |
| CN-103957880-A | Hair treatment agent comprising 4-morpholino-methyl-substituted silicone(s) | HENKEL AG & CO KGAA | 2014-07-30 | — | — | CN | claimed |
| CN-103957883-A | Pretreatment agents for keratin fibers comprising 4-morpholino-methyl-substituted silicone(s) | HENKEL AG & CO KGAA | 2014-07-30 | — | — | CN | claimed |
| CN-101604607-A | Coating composition for interconnection part of electrode and comprise its plasma display | SAMSUNG SDI CO LTD (KR) | 2009-12-16 | — | — | CN | claimed |
| CN-1849121-A | Piperazine derivatives as bradyknin antagonist | AMGEN INC (US) | 2006-10-18 | — | — | CN | claimed |
| CN-1161336-C | Quinoline carboxamides as antiviral agents | �������Ŷ���Լ��������˾ | 2004-08-11 | — | — | CN | claimed |
| CN-1432001-A | 1-aryl-4-oxo-1,4-dihydro-3-quinolinecarboxamides as antiviral agents | UPJOHN CO (US) | 2003-07-23 | — | — | CN | claimed |
| CN-1390211-A | Benzoic ester comprising ethoxyl acyl piperazine substituted oxazolidone compound | UPJOHN CO (US) | 2003-01-08 | — | — | CN | claimed |
| CN-1378537-A | Pyrimidine derivatives | ASTRAZENECA AB (SE) | 2002-11-06 | — | — | CN | claimed |
| CN-1333753-A | Quinoline carboxamides as antiviral agents | UPJOHN CO (US) | 2002-01-30 | — | — | CN | claimed |
| EP-3464321-B1 | PROTEASOME INHIBITORS | MAX PLANCK GESELLSCHAFT (DE) | 2023-01-25 | — | — | EP | disclosed |
| US-11345724-B2 | Proteasome inhibitors | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2022-05-31 | — | — | US | disclosed |
| CN-1038583-C | Acylphenylglycine derivative and preventive and remedy for diseases caused by increased collagenase activity containing said compound as active ingredient | KANEBO LTD (JP) | 1998-06-03 | — | — | CN | disclosed |
| CN-1133034-A | Acylphenylglycine derivative and preventive or remedy for diseases caused by increased collagenase activity containing the same as active ingredient | KANEBO LTD (JP) | 1996-10-09 | — | — | CN | disclosed |
| CN-1132505-A | Amidine derivatives with nitric oxide synthetase activities | ASTERA CO (SE) | 1996-10-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11345724-B2 | Proteasome inhibitors | PSMB1, PSMB2, PSMB5 | ALDH1A1 3319/4885PKM 2646/4885HSD11B1 1257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.