Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.37 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | TGM2 | P21980 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | F13A1 | P00488 | 1/20 | 0.32 |
| ▸ | TGM1 | P22735 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL423618 | 0.90 | CNR1 (0.42) | KCNH2CACNA1IUSP30ALDH1A1CNR1 | |
| SCHEMBL423896 | 0.79 | CNR1 (0.51) | CNR1SMN1; SMN2 | |
| SCHEMBL426604 | 0.78 | GAA (0.49) | ALDH1A1TGM2 | |
| SCHEMBL426609 | 0.71 | EPHX2 (0.51) | ALDH1A1SMN1; SMN2TGM2 | |
| SCHEMBL423871 | 0.69 | KCNH2 (0.41) | KCNH2CACNA1IUSP30ALDH1A1CNR1 | |
| SCHEMBL423292 | 0.68 | LMNA (0.53) | ALDH1A1CNR1KDM4ESMN1; SMN2 | |
| SCHEMBL424505 | 0.68 | EPHX1 (0.45) | USP30KDM4E | |
| SCHEMBL426646 | 0.67 | FBP1 (0.54) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL16257003 | 0.67 | TGM2 (0.43) | ALDH1A1SMN1; SMN2TGM2F13A1TGM1 | |
| SCHEMBL423241 | 0.66 | SCN9A (0.36) | KCNH2USP30ALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010114181-A1 | ACRYLAMIDE COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2010-10-07 | — | — | WO | disclosed |