Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218463 | 1.00 | THRB (0.48) | THRBLMNACA1CA2MMP1 | |
| SCHEMBL28015789 | 1.00 | THRB (0.48) | THRBLMNACA1CA2MMP1 | |
| SCHEMBL15012282 | 1.00 | THRB (0.48) | THRBLMNACA1CA2MMP1 | |
| SCHEMBL3027405 | 0.97 | THRB (0.43) | THRBLMNA | |
| SCHEMBL7638470 | 0.94 | THRB (0.52) | THRBLMNACA1CA2MMP1 | |
| SCHEMBL5374510 | 0.94 | THRB (0.52) | THRBLMNACA1CA2MMP1 | |
| SCHEMBL4924486 | 0.94 | THRB (0.52) | THRBLMNACA1CA2MMP1 | |
| SCHEMBL5365862 | 0.94 | THRB (0.52) | THRBLMNACA1CA2MMP1 | |
| SCHEMBL1019945 | 0.94 | THRB (0.52) | THRBLMNACA1CA2MMP1 | |
| SCHEMBL8380164 | 0.94 | THRB (0.52) | THRBLMNACA1CA2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197987-B1 | Polyfunctional perhalogenated polyorganosiloxanes and the processes for their preparation | RHONE-BOULING CHIMIE (FR) | 2001-03-06 | — | — | US | disclosed |
| US-6184329-B1 | USED IN ANTIFOAMS, AGENTS FOR LOWERING SURFACE TENSION, DIRT REPELLENTS, ANTIADHESIVES, LUBRICANTS, OLEOPHOBIC AND/OR HYDROPHOBIC AGENTS, COATINGS; STABILITY | RHONE-POULENC CHIMIE (FR) | 2001-02-06 | — | — | US | disclosed |
| US-5331084-A | Chemical intermediates for polyethers | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-19 | — | — | US | disclosed |