Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718947 | 0.88 | XDH (0.56) | XDHSMN1; SMN2RAB9AKDM4EGAA | |
| SCHEMBL7894346 | 0.88 | LMNA (0.48) | XDHSMN1; SMN2RAB9AKDM4EGAA | |
| SCHEMBL3715111 | 0.86 | XDH (0.72) | XDHSMN1; SMN2RAB9AKDM4EGAA | |
| SCHEMBL3704150 | 0.85 | XDH (0.77) | XDHSMN1; SMN2RAB9AKDM4EGAA | |
| SCHEMBL7886674 | 0.81 | XDH (0.50) | XDHSMN1; SMN2RAB9AKDM4EGAA | |
| SCHEMBL3714429 | 0.76 | LMNA (0.48) | XDHRAB9AKDM4EGAAALDH1A1 | |
| SCHEMBL3715991 | 0.75 | KDM4E (0.58) | XDHSMN1; SMN2RAB9AKDM4EGAA | |
| SCHEMBL3714458 | 0.75 | XDH (0.57) | XDHSMN1; SMN2RAB9AKDM4EGAA | |
| SCHEMBL12599357 | 0.75 | KDM4E (0.56) | XDHSMN1; SMN2RAB9AKDM4EGAA | |
| SCHEMBL3705153 | 0.74 | XDH (0.61) | XDHKDM4EALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |