Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.57 |
| ▸ | CDC7 | O00311 | 5/20 | 0.51 |
| ▸ | DBF4 | Q9UBU7 | 5/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3715111 | 0.88 | XDH (0.72) | XDHALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7894346 | 0.87 | LMNA (0.48) | XDHCDC7DBF4TRPM8ALDH1A1 | |
| SCHEMBL3714233 | 0.85 | XDH (0.54) | XDHCDC7DBF4TRPM8ALDH1A1 | |
| SCHEMBL7890220 | 0.82 | CDC7 (0.52) | XDHCDC7DBF4TRPM8ALDH1A1 | |
| SCHEMBL7890859 | 0.81 | CDC7 (0.48) | XDHCDC7DBF4TRPM8ALDH1A1 | |
| SCHEMBL1316281 | 0.79 | CDC7 (0.77) | CDC7DBF4TRPM8ALDH1A1MAPT | |
| SCHEMBL289229 | 0.77 | CDC7 (0.73) | CDC7DBF4TRPM8ALDH1A1MAPT | |
| SCHEMBL3714429 | 0.76 | LMNA (0.48) | XDHCDC7DBF4TRPM8ALDH1A1 | |
| SCHEMBL7893019 | 0.75 | XDH (0.56) | XDHALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7888953 | 0.75 | ALDH1A1 (0.56) | CDC7DBF4TRPM8ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |