Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | TSHR | P16473 | 2/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | CA7 | P43166 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | MGLL | Q99685 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3714000 | 0.85 | GPR183 (0.65) | KMT2AMEN1L3MBTL1LMNACA12 | |
| SCHEMBL7890110 | 0.84 | LMNA (0.73) | USP2ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7071911 | 0.83 | L3MBTL1 (0.61) | USP2ALDH1A1TSHRGAAKMT2A | |
| Acetic Acid SCHEMBL27550437 | 0.80 | L3MBTL1 (0.57) | USP2ALDH1A1TSHRGAAKMT2A | |
| SCHEMBL20804546 | 0.80 | SMN1; SMN2 (0.90) | USP2ALDH1A1TSHRGAAKMT2A | |
| SCHEMBL1946614 | 0.78 | L3MBTL1 (0.75) | KMT2AMEN1L3MBTL1LMNAPOLB | |
| SCHEMBL734913 | 0.78 | CA12 (0.59) | USP2ALDH1A1TSHRGAAKMT2A | |
| SCHEMBL7895294 | 0.78 | KDM4E (0.79) | USP2ALDH1A1TSHRGAAKMT2A | |
| SCHEMBL5011593 | 0.77 | TSHR (0.64) | USP2ALDH1A1TSHRGAALMNA | |
| SCHEMBL3479891 | 0.77 | MAPK9 (0.53) | USP2ALDH1A1TSHRGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010102663-A1 | PIPERAZINE DERIVATIVES FOR USE IN THERAPY | GLAXO GROUP LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |