Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | CA7 | P43166 | 2/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10717731 | 0.86 | CA12 (0.66) | MEN1KMT2AL3MBTL1LMNACA12 | |
| SCHEMBL10674722 | 0.86 | CA12 (0.66) | MEN1KMT2AL3MBTL1LMNACA12 | |
| SCHEMBL7890110 | 0.86 | LMNA (0.73) | MEN1KMT2AL3MBTL1LMNACA12 | |
| Hydrochloric Acid SCHEMBL10719352 | 0.85 | CA12 (0.64) | MEN1KMT2AL3MBTL1LMNACA12 | |
| SCHEMBL1946614 | 0.85 | L3MBTL1 (0.75) | MEN1KMT2AL3MBTL1LMNACA12 | |
| SCHEMBL12761129 | 0.85 | L3MBTL1 (0.75) | MEN1KMT2AL3MBTL1LMNACA12 | |
| SCHEMBL7893660 | 0.85 | USP2 (0.80) | MEN1KMT2AL3MBTL1LMNACA12 | |
| SCHEMBL7077553 | 0.84 | F10 (0.65) | MEN1KMT2AL3MBTL1LMNACA12 | |
| SCHEMBL10717963 | 0.83 | ALDH1A1 (0.67) | GPR183MEN1KMT2AHSP90AA1L3MBTL1 | |
| SCHEMBL10670607 | 0.83 | ALDH1A1 (0.67) | GPR183MEN1KMT2AHSP90AA1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010102663-A1 | PIPERAZINE DERIVATIVES FOR USE IN THERAPY | GLAXO GROUP LIMITED (GB) | 2010-09-16 | — | — | WO | claimed |
| WO-2010102663-A1 | PIPERAZINE DERIVATIVES FOR USE IN THERAPY | GLAXO GROUP LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |