Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | PHGDH | O43175 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | HPGDS | O60760 | 1/20 | 0.52 |
| ▸ | VCP | P55072 | 1/20 | 0.50 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.49 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.48 |
| ▸ | ATP4A | P20648 | 1/20 | 0.48 |
| ▸ | ATP4B | P51164 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7894112 | 0.90 | NPC1 (0.52) | MAPTKDM4EMAPK1KMT2AMEN1 | |
| SCHEMBL8893759 | 0.87 | KMT2A (0.49) | MAPTKDM4EMAPK1KMT2AMEN1 | |
| SCHEMBL27535560 | 0.86 | NPC1 (0.47) | MAPTKDM4EMAPK1KMT2AMEN1 | |
| SCHEMBL7901474 | 0.86 | NPC1 (0.50) | MAPTKDM4EMAPK1NPC1RAB9A | |
| SCHEMBL27426133 | 0.86 | NPC1 (0.50) | MAPTKDM4EMAPK1KMT2AMEN1 | |
| SCHEMBL8894553 | 0.86 | NPC1 (0.50) | MAPTKDM4EMAPK1KMT2AMEN1 | |
| SCHEMBL7901407 | 0.86 | NPC1 (0.55) | MAPTKDM4EMAPK1KMT2AMEN1 | |
| SCHEMBL8895004 | 0.86 | KMT2A (0.48) | MAPTKDM4EMAPK1KMT2AMEN1 | |
| Water SCHEMBL9411708 | 0.85 | NPC1 (0.49) | MAPTKDM4EMAPK1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL27426131 | 0.84 | ADORA3 (0.48) | MAPTKDM4EMAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37094-E1 | Heterocyclic substituted acylaminothiazoles, their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 2001-03-13 | — | — | US | claimed |
| EP-0432040-B2 | Heterocyclic derivatives of acylaminothiazole, their preparation and pharmaceutical compositions containing them | SANOFI SA (FR) | 1997-12-17 | — | — | EP | claimed |
| US-5189049-A | Cholecystokinin and gastrin inhibitors | SANOFI (FR) | 1993-02-23 | — | — | US | claimed |
| US-RE37094-E1 | Heterocyclic substituted acylaminothiazoles, their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 2001-03-13 | — | — | US | disclosed |
| US-5189049-A | Cholecystokinin and gastrin inhibitors | SANOFI (FR) | 1993-02-23 | — | — | US | disclosed |