Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CTRC | Q99895 | 3/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8999829 | 0.80 | MEN1 (0.40) | HPGDCYP2D6MEN1KMT2AALDH1A1 | |
| SCHEMBL4001548 | 0.70 | MMP9 (0.36) | SORT1CALM1MEN1ELANEKMT2A | |
| SCHEMBL4003199 | 0.70 | MMP9 (0.36) | SORT1CALM1MEN1ELANEKMT2A | |
| SCHEMBL6177655 | 0.70 | LTA4H (0.35) | SORT1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6177652 | 0.70 | LTA4H (0.35) | SORT1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4005269 | 0.70 | SMN1; SMN2 (0.57) | HPGDMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4005275 | 0.70 | SMN1; SMN2 (0.57) | HPGDMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6180626 | 0.69 | USP2 (0.34) | SORT1CALM1MEN1ELANEKMT2A | |
| SCHEMBL3999962 | 0.69 | MMP9 (0.35) | SORT1CALM1MEN1ELANEKMT2A | |
| SCHEMBL6178028 | 0.68 | ALDH1A1 (0.39) | HPGDMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180374-B1 | ENANTIOMORPHS; BIOTRANSFORMATION USING ENZYME IN PRESENCE OF AN ALCOHOL OF AN AZLACTONE | CHIROTECH TECHNOLOGY, INC. (GB) | 2001-01-30 | — | — | US | disclosed |
| EP-0726891-B1 | A METHOD FOR PREPARING TERT-LEUCINE AND ANALOGUES THEREOF IN ENANTIOMERIC FORM, AND INTERMEDIATES THEREIN | CHIROTECH TECHNOLOGY LTD (GB) | 1999-02-03 | — | — | EP | disclosed |