Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NTRK1 | P04629 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965826 | 0.84 | TAS1R3 (0.62) | TAS1R3TAS1R1TAS1R2MAPTSMN1; SMN2 | |
| SCHEMBL653099 | 0.84 | TAS1R3 (0.62) | TAS1R3TAS1R1TAS1R2MAPTSMN1; SMN2 | |
| SCHEMBL13450334 | 0.79 | THRB (0.63) | TAS1R3TAS1R1TAS1R2MAPTSMN1; SMN2 | |
| SCHEMBL3720026 | 0.78 | GRIN2B (0.54) | TAS1R3TAS1R1TAS1R2MAPTSMN1; SMN2 | |
| SCHEMBL30008791 | 0.77 | EEF2K (0.69) | TAS1R3TAS1R1TAS1R2MAPTSMN1; SMN2 | |
| SCHEMBL16178762 | 0.77 | SMN1; SMN2 (0.54) | MAPTSMN1; SMN2NTRK1HTTTP53 | |
| SCHEMBL16178800 | 0.76 | RAB9A (0.43) | MAPTSMN1; SMN2NTRK1GRIN2BTP53 | |
| SCHEMBL16178811 | 0.76 | XIAP (0.44) | NTRK1ALDH1A1TP53POLB | |
| SCHEMBL5470045 | 0.76 | TAS1R3 (0.66) | TAS1R3TAS1R1TAS1R2MAPTSMN1; SMN2 | |
| SCHEMBL30008966 | 0.76 | THRB (0.69) | TAS1R3TAS1R1TAS1R2MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010102663-A1 | PIPERAZINE DERIVATIVES FOR USE IN THERAPY | GLAXO GROUP LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |