Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.50 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30365351 | 1.00 | CYP3A4 (0.63) | CYP3A4KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL11689017 | 0.86 | MAPT (0.73) | CYP3A4KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL11689780 | 0.85 | CYP3A4 (0.81) | CYP3A4KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL4299906 | 0.84 | ALDH1A1 (0.70) | KDM4EMAPTALDH1A1LMNANPC1 | |
| Quinoline SCHEMBL9105679 | 0.82 | ALDH1A1 (0.77) | CYP3A4KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL19021034 | 0.81 | KDM4E (0.61) | CYP3A4KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL29712310 | 0.80 | ALDH1A1 (0.58) | CYP3A4KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL30853545 | 0.80 | ALDH1A1 (0.58) | CYP3A4KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL297515 | 0.80 | ALDH1A1 (0.58) | CYP3A4KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL6032927 | 0.80 | LMNA (0.59) | CYP3A4KDM4EMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957891-B1 | REDUCTION OF HAIR GROWTH | GILLETTE CO (US) | 2003-03-19 | — | — | EP | claimed |
| US-6037326-A | APPLYING TO THE SKIN AN INHIBITOR OF A DNA TOPOISOMERASE | GILLETTE COMPANY, THE | 2000-03-14 | — | — | US | claimed |
| EP-0957891-A1 | REDUCTION OF HAIR GROWTH | HANDELMAN, Joseph H. (US) | 1999-11-24 | — | — | EP | claimed |
| WO-1998029086-A1 | REDUCTION OF HAIR GROWTH | HANDELMAN, JOSEPH, H. (US) | 1998-07-09 | — | — | WO | claimed |
| WO-1994003433-A1 | BIOLOGICAL APPLICATIONS OF ALKALOIDS DERIVED FROM THE TUNICATE EUDISTOMA sp. | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1994-02-17 | — | — | WO | claimed |
| US-12291502-B2 | Topoisomerase II-alpha inhibitors and methods of treating cancer using the same | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2025-05-06 | — | — | US | disclosed |
| EP-3168221-B1 | COMPOUND, ORGANIC OPTOELECTRONIC DIODE COMPRISING SAME, AND DISPLAY | SAMSUNG SDI CO LTD (KR) | 2023-06-28 | — | — | EP | disclosed |
| US-20230105776-A1 | Topoisomerase II-alpha Inhibitors and Methods of Treating Cancer Using the Same | UNITED STATES GOVERNMENT | 2023-04-06 | — | — | US | disclosed |
| US-11466021-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2022-10-11 | — | — | US | disclosed |
| EP-3548486-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020205991-A1 | TOPOISOMERASE II-alpha INHIBITORS AND METHODS OF TREATING CANCER USING THE SAME | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2020-10-08 | — | — | WO | disclosed |
| US-20200199138-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-06-25 | — | — | US | disclosed |
| WO-1994003433-A1 | BIOLOGICAL APPLICATIONS OF ALKALOIDS DERIVED FROM THE TUNICATE EUDISTOMA sp. | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1994-02-17 | — | — | WO | disclosed |
| US-5278168-A | Biological applications of alkaloids derived from the tunicate Eudistoma sp. | THE RESEARCH FOUNDATION OF STATE UNIVERISTY OF NEW YORK (US) | 1994-01-11 | — | — | US | disclosed |
| EP-0608215-A4 | QUINOBENZOXAZINE, QUINOBENZOTHIAZINE, AND PYRIDO-ACRIDINE ANTINEOPLASTIC AGENTS. | ABBOTT LAB (US) | 1993-11-11 | — | — | EP | disclosed |
| EP-0608215-A4 | QUINOBENZOXAZINE, QUINOBENZOTHIAZINE, AND PYRIDO-ACRIDINE ANTINEOPLASTIC AGENTS. | ABBOTT LAB (US) | 1993-11-11 | — | — | EP | disclosed |
| WO-1993016702-A1 | QUINOBENZOXAZINE, QUINOBENZOTHIAZINE, AND PYRIDO-ACRIDINE ANTINEOPLASTIC AGENTS | ABBOTT LABORATORIES (US) | 1993-09-02 | — | — | WO | disclosed |
| WO-1993016702-A1 | QUINOBENZOXAZINE, QUINOBENZOTHIAZINE, AND PYRIDO-ACRIDINE ANTINEOPLASTIC AGENTS | ABBOTT LABORATORIES (US) | 1993-09-02 | — | — | WO | disclosed |
| WO-1992003136-A1 | QUINOBENZOXAZINE, QUINOBENZOTHIAZINE, AND PYRIDO-ACRIDINE ANTINEOPLASTIC AGENTS | ABBOTT LABORATORIES (US) | 1992-03-05 | — | — | WO | disclosed |
| WO-1992003136-A1 | QUINOBENZOXAZINE, QUINOBENZOTHIAZINE, AND PYRIDO-ACRIDINE ANTINEOPLASTIC AGENTS | ABBOTT LABORATORIES (US) | 1992-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200199138-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | OR10J3, L1CAM, EPCAM | CYP3A4 933/4885KDM4E 1917/4885MAPT 753/4885 |
| US-20230105776-A1 | Topoisomerase II-alpha Inhibitors and Methods of Treating Cancer Using the Same | TOP2A, TOP1, TOP2B | CYP3A4 1403/4885KDM4E 2961/4885MAPT 2017/4885 |
| US-12291502-B2 | Topoisomerase II-alpha inhibitors and methods of treating cancer using the same | TOP2A, TOP1, TOP2B | CYP3A4 1403/4885KDM4E 2961/4885MAPT 2017/4885 |
| US-11466021-B2 | Materials for organic electroluminescent devices | OR10J3, L1CAM, EPCAM | CYP3A4 933/4885KDM4E 1917/4885MAPT 753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.