Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12545758 | 0.80 | KMT2A (0.49) | ADORA3RAB9AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL1430419 | 0.76 | MAPT (0.67) | L3MBTL1CYP1A2RAB9AMAPTKDM4E | |
| SCHEMBL16481155 | 0.74 | L3MBTL1 (0.48) | L3MBTL1MAPK8MAPK9ADORA3RAB9A | |
| SCHEMBL11119241 | 0.73 | SMN1; SMN2 (0.57) | L3MBTL1CYP1A2RAB9ANPC1TP53 | |
| SCHEMBL9817307 | 0.72 | ALDH1A1 (0.53) | L3MBTL1RAB9AMAPTKDM4ENPC1 | |
| SCHEMBL4112548 | 0.72 | EGFR (0.66) | RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL11294168 | 0.72 | NPC1 (0.47) | L3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9893025 | 0.71 | EGFR (0.48) | RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1022794 | 0.71 | SMN1; SMN2 (0.41) | CYP1A2RAB9AMAPTKDM4EHSD17B10 | |
| SCHEMBL9416888 | 0.70 | EGFR (0.47) | L3MBTL1ADORA3RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373634-B1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARM CO LTD (JP) | 2015-11-11 | — | — | EP | disclosed |
| WO-2010065717-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |