Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4541315 | 0.77 | ATAD2 (0.35) | NOTUMATAD2DAO | |
| SCHEMBL4540866 | 0.77 | ALDH1A1 (0.35) | NOTUMDAOMAPT | |
| SCHEMBL9330869 | 0.75 | ATAD2 (0.46) | NOTUMATAD2 | |
| SCHEMBL13555561 | 0.71 | — | — | |
| SCHEMBL13759885 | 0.70 | KDM4E (0.41) | KDM4EUSP2MAPT | |
| SCHEMBL2115438 | 0.69 | — | — | |
| SCHEMBL16921631 | 0.68 | NOTUM (0.38) | NOTUMATAD2KDM4EMAPT | |
| SCHEMBL2115577 | 0.68 | — | — | |
| SCHEMBL7857021 | 0.67 | DAO (0.45) | NOTUMATAD2DAOKDM4EMEN1 | |
| SCHEMBL15680180 | 0.66 | SRC (0.42) | DAOKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177409-B1 | 2-(ALKYL OR HALOALKYL)-3-HYDROXY PYRAN-4-ONE IS HYDROXYL-PROTECTED, AND REACTED WITH AN AMINO ITOL TO SUBSTITUTED THE INTRACYCLIC OXYGEN OF PYRANONE WITH THE AMINE OF THE AMINO ITOL; IRON(III) CHELATORS FOR BLOOD DISORDERS | INSTITUTO BIOCHIMICO PAVESE PHARMA S.P.A. (IT) | 2001-01-23 | — | — | US | disclosed |