Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TERT | O14746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6930363 | 0.98 | CA1 (0.56) | CA1CA2ALDH1A1L3MBTL1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL6932230 | 0.88 | MLYCD (0.48) | CA1CA2ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL2568204 | 0.85 | CA1 (0.60) | CA1CA2ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL1663647 | 0.84 | CA2 (0.58) | CA1CA2ALDH1A1TERTPOLB | |
| SCHEMBL7895751 | 0.82 | ALDH1A1 (0.64) | CA1CA2ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL758271 | 0.82 | MAPT (0.62) | CA1CA2ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL6932060 | 0.82 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1SMN1; SMN2MAPK1POLB | |
| SCHEMBL7753639 | 0.82 | NPC1 (0.59) | ALDH1A1L3MBTL1SMN1; SMN2MAPK1POLB | |
| SCHEMBL11789125 | 0.79 | ALDH1A1 (0.70) | CA1CA2ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL656903 | 0.79 | MEN1 (0.77) | ALDH1A1MAPK1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859000-B1 | Isoxazole amide and crotonamid derivatives and drug and diagnostic uses thereof | AVENTIS PHARMA GMBH (DE) | 2003-01-22 | — | — | EP | claimed |
| US-6265588-B1 | USE AS PHARMACEUTICALS; AS AN ANTIGEN FOR PRODUCTION OF ANTIBODIES AND IN DIAGNOSIS AND PURIFICATION | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-07-24 | — | — | US | disclosed |
| US-6121479-A | ANTIINFLAMMATORY AND ANTICARCINOGENIC AGENTS; AUTOIMMUNE DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | disclosed |
| US-5977151-A | ANTITUMOR | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |