SCHEMBL9504456

SCHEMBL9504456

CC=Cc1ccccc1Oc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.56
HTT P42858 1/20 0.55
SRD5A2 P31213 3/20 0.49
ELANE P08246 3/20 0.49
SMN1; SMN2 Q16637 1/20 0.48
LMNA P02545 4/20 0.46
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
MAPT P10636 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MAOB P27338 1/20 0.46
POLB P06746 1/20 0.46
TLR4 O00206 1/20 0.46
TLR2 O60603 1/20 0.46
NPC1 O15118 1/20 0.46
BCHE P06276 1/20 0.46
RAB9A P51151 1/20 0.46
ALDH1A1 P00352 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9504448 1.00 GAA (0.56) GAAHTTSRD5A2ELANESMN1; SMN2
SCHEMBL25498288 0.97 GAA (0.55) GAAHTTSRD5A2ELANESMN1; SMN2
SCHEMBL12227188 0.97 GAA (0.55) GAAHTTSRD5A2ELANESMN1; SMN2
SCHEMBL158896 0.97 GAA (0.55) GAAHTTSRD5A2ELANESMN1; SMN2
SCHEMBL29533606 0.97 GAA (0.55) GAAHTTSRD5A2ELANESMN1; SMN2
SCHEMBL29399051 0.97 GAA (0.55) GAAHTTSRD5A2ELANESMN1; SMN2
SCHEMBL158895 0.97 GAA (0.55) GAAHTTSRD5A2ELANESMN1; SMN2
SCHEMBL25498275 0.92 GAA (0.50) GAAHTTSRD5A2ELANESMN1; SMN2
SCHEMBL23484458 0.90 GAA (0.52) GAAHTTSRD5A2ELANESMN1; SMN2
SCHEMBL15753383 0.88 GAA (0.45) GAAHTTSRD5A2ELANESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3350150-B1 ALKENYLPHENOXY-SUBSTITUTED 1,1-DIPHENYLETHYLENES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE EVONIK OPERATIONS GMBH (DE) 2020-02-19 EP disclosed
US-10233139-B2 Alkenylphenoxy-substituted 1,1-diphenylethylenes, processes for their preparation, and their use EVONIK TECHNOCHEMIE GMBH (DE) 2019-03-19 US disclosed
EP-3350150-A1 ALKENYLPHENOXY-SUBSTITUTED 1,1-DIPHENYLETHYLENES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE Evonik Technochemie GmbH (DE) 2018-07-25 EP disclosed
US-20180201561-A1 ALKENYLPHENOXY-SUBSTITUTED 1,1-DIPHENYLETHYLENES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE EVONIK TECHNOCHEMIE GMBH (DE) 2018-07-19 US disclosed
WO-2017045932-A1 ALKENYLPHENOXY-SUBSTITUTED 1,1-DIPHENYLETHYLENES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE EVONIK TECHNOCHEMIE GMBH (DE) 2017-03-23 WO disclosed
EP-3144290-A1 ALKENYLPHENOXY-SUBSTITUTED 1,1-DIPHENYLETHYLENES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE Evonik Technochemie GmbH (DE) 2017-03-22 EP disclosed
EP-0230741-B1 CURABLE RESINS Technochemie GmbH - Verfahrenstechnik (DE) 1993-08-11 EP disclosed
US-4939305-A High fracture toughness TECHNOCHEMIE GMBH (DE) 1990-07-03 US disclosed
US-4917954-A Laminated article from curable resin composition comprising bis maleimide and alkenyl phenyl hydroxy ether TECHNOCHEMIE GMBH (DE) 1990-04-17 US disclosed
US-4871821-A TOUGHNESS TECHNOCHEMIE GMBH (DE) 1989-10-03 US disclosed
US-4789704-A BINDERS FOR COMPOSITES, FILMS, LAMINATES; HIGH FRACTURE TOUGHNESS TECHNOCHEMIE GMBH (DE) 1988-12-06 US disclosed
EP-0230741-A2 Curable resins Technochemie GmbH - Verfahrenstechnik (DE) 1987-08-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180201561-A1 ALKENYLPHENOXY-SUBSTITUTED 1,1-DIPHENYLETHYLENES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE MACF1, COL1A1, PLOD1 GAA 4566/4885HTT 2585/4885SRD5A2 4281/4885
US-10233139-B2 Alkenylphenoxy-substituted 1,1-diphenylethylenes, processes for their preparation, and their use MACF1, COL1A1, PLOD1 GAA 4535/4885HTT 1894/4885SRD5A2 4231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.