Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.59 |
| ▸ | CES1 | P23141 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 5/20 | 0.57 |
| ▸ | CA2 | P00918 | 5/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.55 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.55 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11196196 | 0.91 | F3 (0.60) | ALDH1A1MAPTKDM4ECYP1A2CYP3A4 | |
| SCHEMBL11196194 | 0.91 | F3 (0.60) | ALDH1A1MAPTKDM4ECYP1A2CYP3A4 | |
| SCHEMBL11199460 | 0.83 | KDM4E (0.64) | CES2CES1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL10923878 | 0.83 | PARP10 (0.53) | PARP10PARP2PARP4ALDH1A1MAPT | |
| SCHEMBL10719753 | 0.82 | GSK3B (0.43) | CA1CA2ALDH1A1MAPTKDM4E | |
| SCHEMBL10920836 | 0.81 | ALDH1A1 (0.48) | CES2CES1PARP1ALDH1A1MAPT | |
| SCHEMBL10840477 | 0.81 | CES2 (0.61) | CES2CES1CA1CA2PARP1 | |
| SCHEMBL2122823 | 0.79 | CES2 (0.59) | CES2CES1CA1CA2PARP1 | |
| SCHEMBL11468841 | 0.79 | PARP10 (0.59) | PARP10ALDH1A1MAPTKDM4ECYP1A2 | |
| SCHEMBL10897886 | 0.79 | CES2 (0.67) | CES2CES1PARP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596885-A | Process for the preparation of phenylglyoxylic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1986-06-24 | — | — | US | claimed |
| US-4302583-A | BY HEATING THE CORRESPONDING DIMERIC ACYL CYANIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-11-24 | — | — | US | claimed |
| US-4143068-A | PROCESS FOR THE PREPARATION OF ACYL CYANIDE COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-06 | — | — | US | claimed |
| CN-117136335-A | Photosensitive resin composition | 味之素株式会社 | 2023-11-28 | — | — | CN | disclosed |
| CN-112321544-B | Chiral quaternary carbon cyanide and preparation method thereof | 深圳湾实验室坪山生物医药研发转化中心 | 2023-05-26 | — | — | CN | disclosed |
| CN-112321544-A | Chiral quaternary carbon cyanide and preparation method thereof | 深圳湾实验室坪山生物医药研发转化中心 | 2021-02-05 | — | — | CN | disclosed |
| US-9630933-B2 | Method for producing 1-H-tetrazole derivative | NIPPON SODA CO., LTD. (JP) | 2017-04-25 | — | — | US | disclosed |
| US-9630933-B2 | Method for producing 1-H-tetrazole derivative | NIPPON SODA CO., LTD. (JP) | 2017-04-25 | — | — | US | disclosed |
| US-20150322021-A1 | METHOD FOR PRODUCING 1-H-TETRAZOLE DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 2015-11-12 | — | — | US | disclosed |
| US-20150322021-A1 | METHOD FOR PRODUCING 1-H-TETRAZOLE DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 2015-11-12 | — | — | US | disclosed |
| US-20150158829-A1 | METHOD FOR PRODUCING AZIDE COMPOUND, AND METHOD FOR PRODUCING 1-H-TETRAZOLE DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 2015-06-11 | — | — | US | disclosed |
| EP-0005484-B1 | PROCESS FOR THE PREPARATION OF ACYL CYANIDES | BAYER AG (DE) | 1980-12-10 | — | — | EP | disclosed |
| US-4238412-A | CYANATION OF THE ANHYDRIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | disclosed |
| EP-0005484-A1 | Process for the preparation of acyl cyanides | BAYER AG (DE) | 1979-11-28 | — | — | EP | disclosed |
| US-4143068-A | PROCESS FOR THE PREPARATION OF ACYL CYANIDE COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-06 | — | — | US | disclosed |
| US-4122116-A | HERBICIDES | DEUTSCHE GOLD- UND SILBER- SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1978-10-24 | — | — | US | disclosed |
| US-4108877-A | REACTING ACYL HALIDE WITH COPPER CYANIDE WITH HEATING IN THE PRESENCE OF A CARBOXYLIC ACID NITRILE AND AN ORGANIC SOLVENT | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1978-08-22 | — | — | US | disclosed |
| US-4108875-A | REACTING ACYL HALIDE WITH AN ALKALI METAL CYANIDE AND A COPPER(I) SALT IN THE PRESENCE OF A CARBOXYLIC ACID NITRILE WITH HEATING | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1978-08-22 | — | — | US | disclosed |
| US-4069252-A | Process for the preparation of certain acyl cyanide compounds | BAYER AKTIENGESELLSCHAFT (DT) | 1978-01-17 | — | — | US | disclosed |
| US-3986972-A | HYDROGEN PEROXIDE | AMERICAN CYANAMID COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322021-A1 | METHOD FOR PRODUCING 1-H-TETRAZOLE DERIVATIVE | CBR1, RIF1, CBR3 | CES2 2160/4885CES1 2747/4885CA1 130/4885 |
| US-20150158829-A1 | METHOD FOR PRODUCING AZIDE COMPOUND, AND METHOD FOR PRODUCING 1-H-TETRAZOLE DERIVATIVE | AS3MT, MSMO1, ABL1 | CES2 1018/4885CES1 3326/4885CA1 148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.